Trial design of CAR T cell therapy for autoimmune diseases

Jewell CM, Schett G (2026)

Publication Type: Journal article

Publication year: 2026

DOI: 10.1038/s44222-026-00451-5

Abstract

Technological advancements, including in vivo delivery, RNA payloads, combination treatments, multi-specifics and T cell engagers, as well as gene editing, are expanding CAR T applications from cancer to autoimmune disease. These applications present distinct opportunities for randomized controlled trials of CAR T cell therapies.

Authors with CRIS profile

Georg Schett Lehrstuhl für Innere Medizin III

Involved external institutions

University of Maryland, College Park (UMD) US United States (USA) (US)

How to cite

APA:

Jewell, C.M., & Schett, G. (2026). Trial design of CAR T cell therapy for autoimmune diseases. . https://doi.org/10.1038/s44222-026-00451-5

MLA:

Jewell, Christopher M., and Georg Schett. "Trial design of CAR T cell therapy for autoimmune diseases." (2026).

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