Physics of SPION–Surface Interactions in Fluidic Channels: Implications for Molecular Communication Systems

Xiao K, Thalmayer A, Kirchner J, Fischer G (2026)

Publication Type: Journal article, Original article

Publication year: 2026

Journal

IEEE Transactions on Molecular, Biological and Multi-Scale Communications IEEE

DOI: 10.1109/TMBMC.2026.3686303

Abstract

It is promising to study magnetic drug targeting through molecular communication (MC) frameworks, which model superparamagnetic iron-oxide nanoparticles (SPIONs) as nanoscale information carriers. However, a key factor influencing MC performance, the physics governing SPIONs adhesion to channel surfaces, remains poorly characterized. This study establishes a computational model of SPION dynamics to elucidate the adhesion mechanisms. Our results reveal that the relative balance between van der Waals forces and electrostatic forces is the primary factor determining SPION adhesion behavior. Moreover, we determined the relationship between this balance and the ion concentration of the medium. Based on these insights, we propose strategies to reduce adhesion and thus improve the performance of MC systems.

Authors with CRIS profile

Keyu Xiao Professur für Technische Elektronik Angelika Thalmayer Professur für Technische Elektronik Georg Fischer Professur für Technische Elektronik

Involved external institutions

Fachhochschule Dortmund - University of Applied Sciences DE Germany (DE)

How to cite

APA:

Xiao, K., Thalmayer, A., Kirchner, J., & Fischer, G. (2026). Physics of SPION–Surface Interactions in Fluidic Channels: Implications for Molecular Communication Systems. IEEE Transactions on Molecular, Biological and Multi-Scale Communications. https://doi.org/10.1109/TMBMC.2026.3686303

MLA:

Xiao, Keyu, et al. "Physics of SPION–Surface Interactions in Fluidic Channels: Implications for Molecular Communication Systems." IEEE Transactions on Molecular, Biological and Multi-Scale Communications (2026).

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