Personality dysfunction according to the DSM-5 Alternative Model of Personality Disorders (AMPD) predicts suicide attempts in clinical high-risk adolescents
Zippert LK, Hertel C, Sele S, Reichl C, Cavelti M, Koenig J, Kaess M (2026)
Publication Type: Journal article
Publication year: 2026
Journal
Book Volume: 407
Article Number: 121811
DOI: 10.1016/j.jad.2026.121811
Abstract
Background Both personality traits and personality disorders have been linked to suicide risk in youth. The DSM-5 Alternative Model of Personality Disorders (AMPD) allows dimensional assessment of personality pathology, which may enhance prediction of suicide attempts. A recent study found that personality dysfunction (Criterion A of the AMPD) is associated with past suicide attempts in adolescents. Building on this, the present study aimed to investigate the longitudinal relationship between AMPD personality pathology and suicide attempts in adolescents. Methods Data were drawn from a consecutive clinical cohort study including adolescent patients aged 12 to 18 years ( N = 252, 85% female) engaging in risk-taking and self-harming behaviors. Personality dysfunction, maladaptive personality traits, suicide attempts, and depression severity were assessed using standardized interviews and questionnaires at baseline and at two annual follow-ups. 66% of participants completed any follow-up. A Bayesian Structural Equation Modeling framework was used for data analysis. Results Personality dysfunction predicted suicide attempts over the two-year follow-up (β = 0.38, 95% CI [0.01; 0.73], p = .046). Adding maladaptive personality traits did not add predictive value, while depression severity emerged as a slightly stronger predictor. The effect of personality dysfunction remained stable after accounting for these variables. Conclusions These findings highlight the value of assessing personality dysfunction in adolescent suicide risk evaluation. Within the AMPD framework, personality dysfunction may be more important than maladaptive traits in predicting suicide attempts. However, analyzing distinct personality functioning domains or maladaptive traits may provide further insight into suicide attempt prediction.
Involved external institutions
Switzerland (CH)
Germany (DE)How to cite
APA:
Zippert, L.K., Hertel, C., Sele, S., Reichl, C., Cavelti, M., Koenig, J., & Kaess, M. (2026). Personality dysfunction according to the DSM-5 Alternative Model of Personality Disorders (AMPD) predicts suicide attempts in clinical high-risk adolescents. Journal of Affective Disorders, 407. https://doi.org/10.1016/j.jad.2026.121811
MLA:
Zippert, Lea Kassandra, et al. "Personality dysfunction according to the DSM-5 Alternative Model of Personality Disorders (AMPD) predicts suicide attempts in clinical high-risk adolescents." Journal of Affective Disorders 407 (2026).
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