On the German S3 guideline on perioperative and periinterventional antibiotic prophylaxis Zur S3-Leitlinie „Perioperative und periinterventionelle Antibiotikaprophylaxe“

Müller SK, Hofauer B (2026)

Publication Type: Journal article

Publication year: 2026

Journal

Abstract

In December 2024, the German S3 guideline on perioperative and periinterventional antibiotic prophylaxis (PAP) was published after years of interdisciplinary collaboration. This guideline was developed with the involvement of a delegation from the German Society of Otorhinolaryngology, Head and Neck Surgery, because it is particularly important for our medical specialty: in interdisciplinary comparison, otorhinolaryngologists traditionally prescribe a relatively high number of antibiotics in perioperative settings. The S3 guideline is based on randomized controlled trials and review articles evaluated by the Robert Koch Institute using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology. The aim of this CME article is to present the S3 guideline with a focus on the indications for PAP, its duration, risk assessment, and selection of the appropriate antibiotic. Practical application examples and a dosage table further illustrate these points.

Authors with CRIS profile

Sarina Katrin Ursel Müller-Hübner Department of Otorhinolaryngology – Head and Neck Surgery (HNO-Klinik)

Involved external institutions

Medizinische Universität Innsbruck

Austria (AT)

How to cite

APA:

Müller, S.K., & Hofauer, B. (2026). On the German S3 guideline on perioperative and periinterventional antibiotic prophylaxis Zur S3-Leitlinie „Perioperative und periinterventionelle Antibiotikaprophylaxe“. HNO. https://doi.org/10.1007/s00106-026-01752-2

MLA:

Müller, Sarina Katrin, and Benedikt Hofauer. "On the German S3 guideline on perioperative and periinterventional antibiotic prophylaxis Zur S3-Leitlinie „Perioperative und periinterventionelle Antibiotikaprophylaxe“." HNO (2026).

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