Brake E, Gastiger S, Peter D, Schober L, Stuhlfauth L, Burkovski A (2026)
Publication Type: Journal article
Publication year: 2026
Book Volume: 5
Article Number: 18
Journal Issue: 1
Corynebacterium lactis was isolated from the skin abscess of a companion dog and from raw milk of a cow with unspecific mastitis. As information about the species was scarce and a zoonotic potential could not be excluded, we started a basic characterization of C. lactis strain RW3-42 with respect to antibiotic susceptibility and the response of invertebrate animal model systems to infection. C. lactis showed a number of antimicrobial resistances and is able to colonize Caenorhabditis elegans. In contrast, Galleria mellonella larvae were not impaired by C. lactis. Genome analyses of strain RW2-5 revealed the absence of toxin-encoding genes, and only a rather small number of other virulence factors were found, i.e., SpaA- and SpaH-type pili and the non-fimbrial adhesins DIP0733, DIP1281, DIP1621 and EmbC in addition to a homologue of Salmonella RhuM involved in killing of C. elegans. The results obtained indicate a limited pathogenic potential of the species.
APA:
Brake, E., Gastiger, S., Peter, D., Schober, L., Stuhlfauth, L., & Burkovski, A. (2026). Corynebacterium lactis: Antimicrobial Resistance and Impact on Invertebrate Model Systems. Bacteria, 5(1). https://doi.org/10.3390/bacteria5010018
MLA:
Brake, Ella, et al. "Corynebacterium lactis: Antimicrobial Resistance and Impact on Invertebrate Model Systems." Bacteria 5.1 (2026).
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