Diagnosis and Therapy of EndometriosisGuideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/045, April 2025) Diagnostik und Therapie der Endometriose. Leitlinie der DGGG, OEGGG und SGGG (S2k-Level, AWMF-Registernummer 015/045, April 2025)

Burghaus S, Schäfer SD, Bär KJ, Bartley J, Beckmann M, Behrens A, Beyer K, Bianchi N, Brandes I, Brünahl C, Burandt EC, Chvátal R, Dietzel F, Ditzen B, Drahoåovský J, Eickhoff A, Erlenwein J, Fehm T, Fehr PM, Felberbaum RE, Georgieff R, Grab D, Grimm-Glang D, Hackethal A, Hancke K, Häuser W, Hoopmann M, Houbois C, Krautz C, Krentel H, Künzel K, Linsenbühler S, Manegold-Brauer G, Mayer-Hrusa I, Mechsner S, Meden H, Müller M, Nothacker M, Oppelt P, Oppelt P, Pasiecznyk B, Pogatzki-Zahn E, Renner SP, Röhrig M, Rosenberger D, Ruhland F, Sänger N, Schmid J, Schweppe KW, Siedentopf F, Sirbu H, Speer R, Thorn P, Trufa D, Von Versen-Höynck F, Vogeler F, Weidner K, Wischmann T, Wittek K, Wölfler M, Zraik I, Ulrich UA (2026)

Publication Type: Journal article

Publication year: 2026

Journal

Book Volume: 86

Pages Range: 133-188

Journal Issue: 2

DOI: 10.1055/a-2760-4867

Abstract

Objective The objective of this revised official guideline, published by the German Society for Gynecology and Obstetrics (DGGG) and coordinated in the joint guidelines program of the DGGG, the Austrian Society for Gynecology and Obstetrics (OEGGG), and the Swiss Society for Gynecology and Obstetrics (SGGG), is to provide evidence-based and consensus-based recommendations for the diagnosis, treatment, care, and support of girls and women with confirmed or suspected endometriosis. Methods This S2k guideline was developed through a structured consensus process involving representative members of various professions (37 professional associations, organizations, and self-help groups) and includes 25 statements and 73 recommendations which are based on a systematic literature review (2019-2023) and expert consensus. Recommendations For the first time, the revised guideline has placed a greater focus on individualized, symptom-oriented diagnosis and treatment that combines hormonal, surgical, and multimodal approaches. A significant innovation is the use of transvaginal ultrasound as the central diagnostic procedure for detecting endometriosis. Therapeutically, primary hormone treatment is now recommended as the first choice approach, with surgical interventions and multimodal approaches supplemented on an individual and symptom-oriented basis.

Authors with CRIS profile

Involved external institutions

Clemenshospital Germany (DE) Universitätsklinikum Jena Germany (DE) Universitätsklinikum Leipzig Germany (DE) Evangelische Elisabeth Klinik Germany (DE) Universitätsklinikum Hamburg-Eppendorf (UKE) Germany (DE) Universitätsklinikum Düsseldorf Germany (DE) University of Zurich / Universität Zürich (UZH) Switzerland (CH) Klinikum Stadt Hanau Germany (DE) DRK Deutsches Schmerz-Zentrum Mainz / German Pain Center Germany (DE) Klinikverbund Allgäu Germany (DE) Universitätsklinikum Ulm Germany (DE) AMEOS Reha Klinikum Ratzeburg Germany (DE) Universitätsklinikum Tübingen Germany (DE) profertilita - Kinderwunschklinik Germany (DE) Klinik Bad Trissl Germany (DE) Universitätsspital Basel Switzerland (CH) Endometriose Vereinigung Austria Austria (AT) Charité - Universitätsmedizin Berlin Germany (DE) Inselspital, Universitätsspital Bern Switzerland (CH) AWMF-Institut für Medizinisches Wissensmanagement (AWMF-IMWi) Germany (DE) Kepler Universitätsklinikum (KUK) Austria (AT) Universitätsklinikum Münster Germany (DE) Klinikverbund Südwest (Sindelfingen-Böblingen, Calw, Nagold, Leonberg, Herrenberg) Germany (DE) Endometriose-Vereinigung Deutschland Germany (DE) Gynäkologie Kompetenzzentrum Stralsund: gSUND Germany (DE) Universitätsklinikum Bonn Germany (DE) Endo-Help Schweizerische Endometriose-Vereinigung Switzerland (CH) Stiftung Endometriose-Forschung Germany (DE) Universitätsklinikum Augsburg Germany (DE) Medizinische Hochschule Hannover (MHH) / Hannover Medical School Germany (DE) MSH Medical School Hamburg - Fachhochschule für Gesundheit und Medizin Germany (DE) Kantonsspital Graubünden Switzerland (CH) Frauenklinik an der Elbe Germany (DE) Medizinisches Versorgungszentrum St. Johann GmbH Zentrum für Schmerztherapie Germany (DE) Universitätsklinikum Köln Germany (DE) Klinikum Aschaffenburg-Alzenau Germany (DE) Ärztliche Gesellschaft zur Gesundheitsförderung (ÄGGF) Germany (DE) Universitätsklinikum Carl Gustav Carus Dresden Germany (DE) Ruprecht-Karls-Universität Heidelberg Germany (DE) Medizinische Universität Graz Austria (AT) Kliniken Essen-Mitte Germany (DE) Vivantes - Netzwerk für Gesundheit GmbH Germany (DE)

How to cite

APA:

Burghaus, S., Schäfer, S.D., Bär, K.J., Bartley, J., Beckmann, M., Behrens, A.,... Ulrich, U.A. (2026). Diagnosis and Therapy of EndometriosisGuideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/045, April 2025) Diagnostik und Therapie der Endometriose. Leitlinie der DGGG, OEGGG und SGGG (S2k-Level, AWMF-Registernummer 015/045, April 2025). Geburtshilfe und Frauenheilkunde, 86(2), 133-188. https://doi.org/10.1055/a-2760-4867

MLA:

Burghaus, Stefanie, et al. "Diagnosis and Therapy of EndometriosisGuideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/045, April 2025) Diagnostik und Therapie der Endometriose. Leitlinie der DGGG, OEGGG und SGGG (S2k-Level, AWMF-Registernummer 015/045, April 2025)." Geburtshilfe und Frauenheilkunde 86.2 (2026): 133-188.

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