An introduction to BASIC Guide: human biomonitoring and surveillance of chemical exposure in occupational settings.

Zare Jeddi M, Jones K, Leese E, Fustinoni S, Galea KS, Santonen T, Porras SP, Hopf NB, Göen T, Bader M, Tranfo G, Tristram A, Iavicoli I, Leso V, Koch HM, Pasanen-Kase R, Boogaard PJ, Persoons R, Esteban-López M, Verpaele S, Kasiotis KM, Machera K, Carrieri M, Palmen N, Duca RC, Van Nieuwenhuyse A, Gonzales M, Haynes EN, Viegas S, Bessems J, Makris KC, Connolly A, Teixeira JP, Chung MK, Parsons PJ, Kumar E, Lin EZ, Kil J, Kwon JH, Tavares AM, Vekic AM, Rezende GHdSe, Scheepers PT (2026)


Publication Type: Journal article, Editorial

Publication year: 2026

Journal

Book Volume: 70

Journal Issue: 2

DOI: 10.1093/annweh/wxaf074

Abstract

Human biomonitoring (HBM) complements air and surface measurements by integrating exposure from all routes and sources, strengthening occupational exposure assessment and control. In occupational settings, HBM can quantify exposure during routine work and nonroutine activities, evaluate controls, investigate incidents (potential overexposures), and support medical surveillance. To use HBM to its full potential, occupational health and safety professionals (OHPs) should adopt harmonized biomonitoring approaches reflecting best practice. This short communication presents the BASIC Guide series (Human Biomonitoring and Surveillance of Chemical Exposure in Occupational Settings), initiated by the International Society of Exposure Science Human Biomonitoring working group (ISES Europe HBM WG) as an integral part of the HBM Global Network. These chemical-specific practical documents operationalize the OECD (Organisation for Economic Co-operation and Development) occupational biomonitoring guidance, supporting the consistent implementation of exposure biomonitoring programs. Each BASIC Guide provides clear instructions on biomarker selection, sample handling, analytical methods, quality assurance, and result interpretation and communication. By translating international frameworks into actionable protocols, the BASIC Guides improve reproducibility and regulatory alignment in occupational HBM and enable more defensible exposure assessments worldwide.

Authors with CRIS profile

Involved external institutions

Netherlands National Institute for Public Health and the Environment / Rijksinstituut voor Volksgezondheid en Milieu (RIVM) NL Netherlands (NL) National Health Laboratory (LNS) / Laboratoire national de santé LU Luxembourg (LU) Tulane University US United States (USA) (US) University of Kentucky US United States (USA) (US) New University of Lisbon / Universidade Nova de Lisboa PT Portugal (PT) Flemish Institute for Technological Research / Vlaamse Instelling voor Technologisch Onderzoek (VITO) BE Belgium (BE) Cyprus University of Technology (CUT) / Τεχνολογικό Πανεπιστήμιο Κύπρου CY Cyprus (CY) University College Dublin (UCD) IE Ireland (IE) Universidade Federal de Minas Gerais (UFMG) BR Brazil (BR) National Institute for Insurance against Accidents at Work / Istituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro (INAIL) IT Italy (IT) Benaki Phytopathological Institute (BPI) / Μπενάκειο Φυτοπαθολογικό Ινστιτούτο GR Greece (GR) University of Padua / Universita degli Studi di Padova IT Italy (IT) Università degli Studi di Napoli Federico II IT Italy (IT) Institut für Prävention und Arbeitsmedizin der Deutschen Gesetzlichen Unfallversicherung, Institut der Ruhr-Universität Bochum (IPA) DE Germany (DE) Staatsekretariat für Wirtschaft / Secrétariat d'État à l'économie / Segreteria di Stato dell'economia / State Secretariat for Economic Affairs (SECO) CH Switzerland (CH) Wageningen University & Research NL Netherlands (NL) University of Grenoble Alpes (UGA) / Université de Grenoble FR France (FR) Instituto de Salud Carlos III (Institute of Health Carlos III, ISCIII) ES Spain (ES) Nickel Institute (USA) US United States (USA) (US) Radboud University Nijmegen NL Netherlands (NL) Wadsworth Center US United States (USA) (US) Savonia University of Applied Sciences / Savonia-ammattikorkeakoulu FI Finland (FI) Yale University US United States (USA) (US) National Institute of Environmental Research / 국립환경과학원 KR Korea, Republic of (KR) National Institute of Health Dr. Ricardo Jorge (INSA) / Instituto Nacional de Saúde Dr. Ricardo Jorge PT Portugal (PT) Shell NL Netherlands (NL) HSE Health and Safety Executive GB United Kingdom (GB) Università degli studi di Milano IT Italy (IT) IOM Institute of Occupational Medicine GB United Kingdom (GB) Finnish Institute of Occupational Health (FIOH) / Työterveyslaitos (TTL) FI Finland (FI) Lausanne University Hospital / Centre hospitalier universitaire vaudois (CHUV) CH Switzerland (CH) BASF SE DE Germany (DE) Catholic University of the Sacred Heart / Università Cattolica del Sacro Cuore IT Italy (IT) The Chinese University of Hong Kong (CUHK) CN China (CN) Korea University / 고려대학교 KR Korea, Republic of (KR)

How to cite

APA:

Zare Jeddi, M., Jones, K., Leese, E., Fustinoni, S., Galea, K.S., Santonen, T.,... Scheepers, P.T. (2026). An introduction to BASIC Guide: human biomonitoring and surveillance of chemical exposure in occupational settings. Annals of Work Exposures and Health, 70(2). https://doi.org/10.1093/annweh/wxaf074

MLA:

Zare Jeddi, Maryam, et al. "An introduction to BASIC Guide: human biomonitoring and surveillance of chemical exposure in occupational settings." Annals of Work Exposures and Health 70.2 (2026).

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