Multidisciplinary guidelines on renal replacement therapy in intensive care medicine

Meersch-Dini M, Abu-Tair M, Bayer M, Brinkmann A, Bellmann R, Brunkhorst F, Custodis F, Czock D, Frey O, Galle J, Hermes C, Joannidis M, John S, Jörres A, Kerz T, Kindgen-Milles D, Koczor M, Kram R, Kuhlmann M, Oppert M, Schlieper G, Schmitz M, Zarbock A, Willam C (2026)

Publication Type: Journal article, Review article

Publication year: 2026

Journal

Book Volume: 30

Pages Range: 46-

Journal Issue: 1

DOI: 10.1186/s13054-025-05817-6

Abstract

BACKGROUND: Renal replacement therapy (RRT) is frequently used in critically ill patients with acute kidney injury (AKI). Here, we provide guidelines for the management of RRT in critically ill patients on the intensive care unit (ICU). METHODS: We convened a systemic literature research and a Delphi process with a bi-national multidisciplinary consensus panel including 22 clinicians of 12 different German-speaking societies (Germany and Austria) with expertise in RRT. This structured guideline process was the basis for the evidence-based statements and recommendations. RESULTS: We identified seven clinical areas needing guidance: (1) start, (2) modality (diffusion and convection), (3) continuous/ intermittent, (4) anticoagulation, (5) dose (6) pharmacotherapy, (7) stopping criteria. The consensus produced 73 statements and recommendations regarding key clinical areas, the most important 47 statements and recommendations are summarized in this overview. CONCLUSIONS: This evidence-based bi-national guideline should provide physicians with guidance for delivering best practice to critically ill patients with a dialysis-dependent AKI.

Authors with CRIS profile

Involved external institutions

Universitätsklinikum Jena Germany (DE) Klinikum Saarbrücken Germany (DE) Universitätsklinikum Heidelberg Germany (DE) Klinikum Heidenheim / General Hospital of Heidenheim Germany (DE) Märkische Kliniken (Klinikum Lüdenscheid, Stadtklinik Werdohl) Germany (DE) Hochschule für Angewandte Wissenschaften Hamburg (HAW) Germany (DE) Medizinische Universität Innsbruck Austria (AT) Klinikum Nürnberg Germany (DE) Universität Witten/Herdecke Germany (DE) Universitätsmedizin der Johannes Gutenberg-Universität Mainz Germany (DE) Universitätsklinikum Düsseldorf Germany (DE) Bundesverband Niere e.V. Germany (DE) Vivantes - Netzwerk für Gesundheit GmbH Germany (DE) Klinikum Ernst von Bergmann Germany (DE) Städtisches Klinikum Solingen Germany (DE) Universitätsklinikum Münster Germany (DE) Evangelisches Klinikum Bethel Germany (DE) Asklepios Kliniken Germany (DE)

How to cite

APA:

Meersch-Dini, M., Abu-Tair, M., Bayer, M., Brinkmann, A., Bellmann, R., Brunkhorst, F.,... Willam, C. (2026). Multidisciplinary guidelines on renal replacement therapy in intensive care medicine. Critical Care, 30(1), 46-. https://doi.org/10.1186/s13054-025-05817-6

MLA:

Meersch-Dini, Melanie, et al. "Multidisciplinary guidelines on renal replacement therapy in intensive care medicine." Critical Care 30.1 (2026): 46-.

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