Low-dose aspirin has no impact on systemic level of serine protease inhibitors in healthy volunteers
Wex T, Treiber G, Link A, Wex H, Malfertheiner P (2009)
Publication Type: Journal article
Publication year: 2009
Journal
Book Volume: 153
Pages Range: 272-274
Journal Issue: 6
DOI: 10.1016/j.trsl.2009.03.001
Abstract
Low-dose aspirin (100 mg/day) was recently found to increase serum levels of alpha-1 protease inhibitor (A1-PI). Here, we studied the serum levels of 2 major serine protease inhibitors, A1-PI and serine leukocyte protease inhibitor (SLPI), in 10 Helicobacter pylorinegative healthy volunteers (HVs) treated with low-dose aspirin alone and in combination with other drugs.1 Neither the treatment with low-dose aspirin alone or in combination altered serum levels of both serine protease inhibitors. The previously described increase of A1-PI levels by low-dose aspirin was most likely caused by multiple endoscopies within a few days, which caused a systemic stress response. © 2009 Mosby, Inc. All rights reserved.
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Germany (DE)How to cite
APA:
Wex, T., Treiber, G., Link, A., Wex, H., & Malfertheiner, P. (2009). Low-dose aspirin has no impact on systemic level of serine protease inhibitors in healthy volunteers. Translational Research, 153(6), 272-274. https://doi.org/10.1016/j.trsl.2009.03.001
MLA:
Wex, Thomas, et al. "Low-dose aspirin has no impact on systemic level of serine protease inhibitors in healthy volunteers." Translational Research 153.6 (2009): 272-274.
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