Radiation therapy for solitary plasmacytoma or multiple myeloma Strahlentherapie bei solitärem Plasmozytom oder multiplem Myelom
Corradini S, Belka C, Plasswilm L (2010)
Publication Type: Journal article
Publication year: 2010
Journal
Book Volume: 16
Pages Range: 294-297
Journal Issue: 3
DOI: 10.1007/s00761-010-1787-9
Abstract
The treatment of choice for solitary plasmacytoma is radiation therapy. The local response rate exceeds 90%. Solitary plasmacytoma is characterized by the neoplastic proliferation of a single clone of plasma cells involving invasion of skeletal structures or extramedullary soft tissues. Progression to multiple myeloma is more common in solitary plasmacytoma of the bone than in extramedullary plasmacytoma. In the treatment of multiple myeloma radiotherapy is effective in palliating local symptoms, such as painful bone metastases, radiculopathy and spinal cord compression. Long-course radiotherapy (10x3 Gy, 20x2 Gy) results in better outcome of pain relief, recalcification rates and local control rates. Patients with a poor survival prognosis benefit from short-course radiotherapy (1x8 Gy, 4x5 Gy). Total body radiation as part of conditioning protocols prior to autologous blood stem cell transplantation is no longer a treatment of choice. © Springer-Verlag 2010.
Involved external institutions
Germany (DE)How to cite
APA:
Corradini, S., Belka, C., & Plasswilm, L. (2010). Radiation therapy for solitary plasmacytoma or multiple myeloma Strahlentherapie bei solitärem Plasmozytom oder multiplem Myelom. Onkologe, 16(3), 294-297. https://doi.org/10.1007/s00761-010-1787-9
MLA:
Corradini, S., C. Belka, and L. Plasswilm. "Radiation therapy for solitary plasmacytoma or multiple myeloma Strahlentherapie bei solitärem Plasmozytom oder multiplem Myelom." Onkologe 16.3 (2010): 294-297.
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