ILAE neuroimaging task force highlight: Tuberous sclerosis complex-related epilepsy
Chen X, Archer J, Bernhardt BC, Caciagli L, Cendes F, Chinvarun Y, Concha L, Federico P, Gaillard WD, Kobayashi E, Ogbole G, Rampp S, Vaudano AE, Wang ZI, Winston GP, Wang S (2025)
Publication Type: Journal article
Publication year: 2025
Journal
DOI: 10.1002/epd2.70087
Abstract
The ILAE Neuroimaging Task Force publishes educational case reports that highlight basic aspects of neuroimaging in epilepsy consistent with the ILAE's educational mission. Tuberous sclerosis complex (TSC) is a rare, complex, and multisystem autosomal dominant genetic disorder that arises from variations in the TSC1 or TSC2 genes. While characterized by a wide range of clinical manifestations, TSC commonly presents with epilepsy, which is a clinically challenging feature of the condition. Neuroimaging plays a pivotal role in the early diagnosis, screening, and long-term monitoring of TSC patients. CT serves as the first-line imaging tool in emergency settings; yet MRI is the primary diagnostic modality for TSC. In this report, we present two patients with TSC-related epilepsy and analyze their neuroimaging findings. We also address the diagnostic and therapeutic challenges faced by TSC patients with epilepsy.
Authors with CRIS profile
Involved external institutions
Second Affiliated Hospital of Zhejiang University (SAHZU) / 浙江大学 医学院 附属第二医院
China (CN)
The University of Melbourne
Australia (AU)
McConnell Brain Imaging Centre (BIC)
Canada (CA)
Inselspital, Universitätsspital Bern
Switzerland (CH)
Universidade Estadual de Campinas (UNICAMP) / University of Campinas
Brazil (BR)
Phramongkutklao College of Medicine (PCM) / วิทยาลัยแพทยศาสตร์พระมงกุฎเกล้า
Thailand (TH)
National Autonomous University of Mexico / Universidad Nacional Autónoma de México (UNAM)
Mexico (MX)
University of Calgary
Canada (CA)
George Washington University (GWU)
United States (USA) (US)
University of Texas Southwestern Medical Center (UT Southwestern)
United States (USA) (US)
University of Ibadan
Nigeria (NG)
Università degli Studi di Modena e Reggio Emilia (UNIMORE)
Italy (IT)
Cleveland Clinic
United States (USA) (US)
Queen's University
Canada (CA)
China (CN)
The University of Melbourne
Australia (AU)
McConnell Brain Imaging Centre (BIC)
Canada (CA)
Inselspital, Universitätsspital Bern
Switzerland (CH)
Universidade Estadual de Campinas (UNICAMP) / University of Campinas
Brazil (BR)
Phramongkutklao College of Medicine (PCM) / วิทยาลัยแพทยศาสตร์พระมงกุฎเกล้า
Thailand (TH)
National Autonomous University of Mexico / Universidad Nacional Autónoma de México (UNAM)
Mexico (MX)
University of Calgary
Canada (CA)
George Washington University (GWU)
United States (USA) (US)
University of Texas Southwestern Medical Center (UT Southwestern)
United States (USA) (US)
University of Ibadan
Nigeria (NG)
Università degli Studi di Modena e Reggio Emilia (UNIMORE)
Italy (IT)
Cleveland Clinic
United States (USA) (US)
Queen's University
Canada (CA)
How to cite
APA:
Chen, X., Archer, J., Bernhardt, B.C., Caciagli, L., Cendes, F., Chinvarun, Y.,... Wang, S. (2025). ILAE neuroimaging task force highlight: Tuberous sclerosis complex-related epilepsy. Epileptic Disorders. https://doi.org/10.1002/epd2.70087
MLA:
Chen, Xiao, et al. "ILAE neuroimaging task force highlight: Tuberous sclerosis complex-related epilepsy." Epileptic Disorders (2025).
BibTeX: Download