Molecular Tumour Boards for Urological Tumours: Hope or Disappointment? Molekulares Tumorboard bei urologischen Tumoren: Hoffnung oder Enttäuschung?

Gaisa NT, Eckstein M, Casuscelli J, Kalogirou C, Zschäbitz S, Dörffer N, Reis H (2025)

Publication Type: Journal article, Review article

Publication year: 2025

Journal

Aktuelle Urologie Georg Thieme Verlag

DOI: 10.1055/a-2651-1738

Abstract

In addition to the traditional, evidence-based, guidelinedriven one-size-fits-all treatment approach, personalised oncological therapy has been gaining increasing importance over the past decade. The central element in this process is a comprehensive molecular pathological analysis of the patient's tumour tissue, followed by interdisciplinary evaluation of the results and their translation into a patient-specific, therapeutic strategy within the framework of the molecular tumour board. These specialised molecular tumour boards are associated with substantial financial, time and personnel resources, as well as highly specialized expertise, and are therefore typically established only at university hospitals or major cancer centres. Despite the high prevalence of urological tumours, very few uro-oncological patient cases are discussed in the molecular tumour boards. In addition, the balance between the resources required and the benefits is often viewed critically. This review article aims to outline the target group, purpose, funding, and operational structure of molecular tumour boards in order to critically assess the situation and effectiveness in uro-oncology.

Authors with CRIS profile

Markus Eckstein Institute of Pathology

Involved external institutions

Universitätsklinikum Ulm DE Germany (DE) Klinikum der Universität München DE Germany (DE) Julius-Maximilians-Universität Würzburg DE Germany (DE) Universitätsklinikum Heidelberg DE Germany (DE) Universitätsklinikum Frankfurt am Main (KGU) DE Germany (DE)

How to cite

APA:

Gaisa, N.T., Eckstein, M., Casuscelli, J., Kalogirou, C., Zschäbitz, S., Dörffer, N., & Reis, H. (2025). Molecular Tumour Boards for Urological Tumours: Hope or Disappointment? Molekulares Tumorboard bei urologischen Tumoren: Hoffnung oder Enttäuschung? Aktuelle Urologie. https://doi.org/10.1055/a-2651-1738

MLA:

Gaisa, Nadine Therese, et al. "Molecular Tumour Boards for Urological Tumours: Hope or Disappointment? Molekulares Tumorboard bei urologischen Tumoren: Hoffnung oder Enttäuschung?" Aktuelle Urologie (2025).

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