Germanium-containing mesoporous bioactive glass nanoparticles (MBGNs) as a new member of the MBGNs family: Synthesis and preliminary characterization

Nawaz Q, Varlik E, Mutlu N, Michálek M, Boccaccini AR (2025)

Publication Type: Journal article

Publication year: 2025

Journal

MRS Communications Cambridge University Press

DOI: 10.1557/s43579-025-00791-0

Abstract

SiO2-CaO-based Germanium containing mesoporous bioactive glass nanoparticles (MBGNs) were synthesized using a microemulsion-assisted sol–gel method. SEM micrographs revealed the spherical morphology of both particle types (with and without Ge), while EDX results confirmed the presence of Ge in the nanoparticles. Structural analysis indicated partial crystallinity in Ge-containing MBGNs due to the presence of GeO2. Preliminary cell biology results indicated that the release of Ge ions from Ge-MBGNs significantly improved cell viability (of osteoblast-like osteosarcoma MG-63 cells) after 48 h. The initial results indicate that Ge-containing MBGNs are promising biomaterials and should be further investigated in bone tissue regeneration approaches involving biologically active ions.

Authors with CRIS profile

Qaisar Nawaz Lehrstuhl für Interfaces und Partikeltechnologie (LFG) Ertugrul Varlik Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Trenčianska univerzita Alexandra Dubčeka v Trenčíne SK Slovakia (SK)

How to cite

APA:

Nawaz, Q., Varlik, E., Mutlu, N., Michálek, M., & Boccaccini, A.R. (2025). Germanium-containing mesoporous bioactive glass nanoparticles (MBGNs) as a new member of the MBGNs family: Synthesis and preliminary characterization. MRS Communications. https://doi.org/10.1557/s43579-025-00791-0

MLA:

Nawaz, Qaisar, et al. "Germanium-containing mesoporous bioactive glass nanoparticles (MBGNs) as a new member of the MBGNs family: Synthesis and preliminary characterization." MRS Communications (2025).

BibTeX: Download