Intermittent preventive treatment, malaria, HIV, hepatitis and pregnancy outcomes in Nigerian women: a cross-sectional study in two healthcare facilities
Chukwuanukwu RC, Eleje GU, Menkiti FE, Ikpeze GC, Mbachu CN, Obiegbu NP, Ogbomade CC, Anyaegbu HI, Ehiaghe AF, Ezeagwuna DA, Efobi CC, Egwuatu EC, Orjinta KK, James JE, Agbanu CMK, Onubuogu CU, Ezenwa OB, Okafor CD, Onah KS, Chukwuanukwu TO (2025)
Publication Type: Journal article
Publication year: 2025
Journal
Book Volume: 25
Article Number: 809
Journal Issue: 1
DOI: 10.1186/s12884-025-07943-z
Abstract
Background: Malaria infection during pregnancy remains a public health concern. Malaria prevention strategies, including chemoprevention, are recommended during pregnancy. This study was conducted to assess the use of intermittent preventive treatment for malaria during pregnancy (IPTp), the prevalence of malaria, HIV, and hepatitis infections and the occurrence of premature rupture of membranes (PROM) among pregnant women in two healthcare facilities in south-eastern Nigeria. Methods: A dual hospital-based cross-sectional study was conducted in two hospitals in Anambra State, Nigeria. Pregnant women who provided informed consent were recruited. Blood samples were collected to test for HIV, malaria, hepatitis B and C virus infections. Results: Among the 134 participants enrolled, 8 (5.97%) tested positive for malaria, 5 (3.73%) for HIV, and 6 (4.47%) for hepatitis B; preeclampsia was observed in 5 women (3.73%), and 3 (2.24%) experienced PROM. The use of IPTp was relatively high at 73.9%. Preterm deliveries accounted for 5.2% of the cases. Conclusion: A lower prevalence of malaria was observed in this study than in previous reports in the region, likely due to the high implementation of IPTp. These findings emphasize the role of IPTp in reducing malaria among pregnant women and provide useful data on HIV, hepatitis and PROM prevalence in the study population.
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Nigeria (NG)How to cite
APA:
Chukwuanukwu, R.C., Eleje, G.U., Menkiti, F.E., Ikpeze, G.C., Mbachu, C.N., Obiegbu, N.P.,... Chukwuanukwu, T.O. (2025). Intermittent preventive treatment, malaria, HIV, hepatitis and pregnancy outcomes in Nigerian women: a cross-sectional study in two healthcare facilities. BMC Pregnancy and Childbirth, 25(1). https://doi.org/10.1186/s12884-025-07943-z
MLA:
Chukwuanukwu, Rebecca Chinyelu, et al. "Intermittent preventive treatment, malaria, HIV, hepatitis and pregnancy outcomes in Nigerian women: a cross-sectional study in two healthcare facilities." BMC Pregnancy and Childbirth 25.1 (2025).
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