From Steady to Pulsatile Flow in Molecular Communication: Propagation of Nanoparticles in Mid-sized Arteries

Wille L, Kirchner J (2025)

Publication Language: English

Publication Type: Conference contribution, Conference Contribution

Publication year: 2025

Event location: University of Catania, Catania, Italy IT

Abstract

The interplay of particle propagation due to fluid convection has been subject to extensive research in the areas
of molecular communication (MC) and magnetic drug targeting (MDT). Although a lot of models have been developed already, often the time-varying nature of the background flow and the elasticity of the channel walls have been neglected. We propose a simulation-based analysis of particle propagation in the radial
artery under pulsatile flow in comparison to classical laminar flow. The effect of elastic channel walls compared to rigid walls is investigated. Our results reveal that in the case of pulsatile flow, the channel impulse response is formed by a series of sharp peaks synchronous to the cardiac cycle instead of the long-tailed shape of laminar flow. In particular, 70% of particle movement occurs in the first 30% of each cardiac cycle. The results indicate
a strong impact of pulsatile flow on inter-symbol interference and thus the design of demodulation algorithms in MC as well as on the design of steering approaches in MDT.

Authors with CRIS profile

Luiz Wille Lehrstuhl für Intelligente Technische Elektronik und Systeme Jens Kirchner Lehrstuhl für Intelligente Technische Elektronik und Systeme

How to cite

APA:

Wille, L., & Kirchner, J. (2025). From Steady to Pulsatile Flow in Molecular Communication: Propagation of Nanoparticles in Mid-sized Arteries. In Proceedings of the 9th Workshop on Molecular Communications. University of Catania, Catania, Italy, IT.

MLA:

Wille, Luiz, and Jens Kirchner. "From Steady to Pulsatile Flow in Molecular Communication: Propagation of Nanoparticles in Mid-sized Arteries." Proceedings of the 9th Workshop on Molecular Communications, University of Catania, Catania, Italy 2025.

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