From Steady to Pulsatile Flow in Molecular Communication: Propagation of Nanoparticles in Mid-sized Arteries

Wille L, Pfannenmüller C, Kirchner J (2025)

Publication Language: English

Publication Type: Journal article

Publication year: 2025

Journal

IEEE Transactions on Molecular, Biological and Multi-Scale Communications IEEE

Event location: University of Catania, Catania, Italy

DOI: 10.1109/TMBMC.2025.3608558

Open Access Link: https://doi.org/10.1109/TMBMC.2025.3608558

Abstract

The interplay of particle propagation due to fluid convection has been subject to extensive research in the areas of MC and MDT. Although a lot of models have been developed already, often the time-varying nature of the background flow and the elasticity of the channel walls have been neglected. We propose a simulation-based analysis of particle propagation in the radial artery under pulsatile flow in comparison to classical laminar flow. The effect of elastic channel walls compared to rigid walls is investigated. Our results reveal that in the case of pulsatile flow, the CIR is formed by a series of sharp peaks synchronous to the cardiac cycle instead of the long-tailed shape of laminar flow. In particular, 70% of particle movement occurs in the first 30% of each cardiac cycle. The results indicate a strong impact of pulsatile flow on inter-symbol interference and thus the design of demodulation algorithms in MC as well as on the design of steering approaches in MDT.

Authors with CRIS profile

Luiz Wille Lehrstuhl für Intelligente Technische Elektronik und Systeme Christof Pfannenmüller Lehrstuhl für Intelligente Technische Elektronik und Systeme Jens Kirchner Lehrstuhl für Intelligente Technische Elektronik und Systeme

Related research project(s)

Synthetic Molecular Communications Across Different Scales: From Theory to Experiments (SyMoCADS) June 1, 2024 - May 31, 2029

How to cite

APA:

Wille, L., Pfannenmüller, C., & Kirchner, J. (2025). From Steady to Pulsatile Flow in Molecular Communication: Propagation of Nanoparticles in Mid-sized Arteries. IEEE Transactions on Molecular, Biological and Multi-Scale Communications. https://doi.org/10.1109/TMBMC.2025.3608558

MLA:

Wille, Luiz, Christof Pfannenmüller, and Jens Kirchner. "From Steady to Pulsatile Flow in Molecular Communication: Propagation of Nanoparticles in Mid-sized Arteries." IEEE Transactions on Molecular, Biological and Multi-Scale Communications (2025).

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