Grötsch B, Bozec A, Schett G (2025)
Publication Language: English
Publication Type: Book chapter / Article in edited volumes
Publication year: 2025
Publisher: Humana Press Inc.
Edited Volumes: Bone Research Protocols
Series: Methods in Molecular Biology
City/Town: New York, NY
Book Volume: 2885
Pages Range: 345-357
DOI: 10.1007/978-1-0716-4306-8_18
Mice models induced by immunization are used to study rheumatoid arthritis (RA) and its molecular mechanisms. In this article, we describe three models that mimic the clinical symptoms of human RA and can be applied to genetically modified mice. The collagen-induced arthritis (CIA), K/BxN serum-induced arthritis (SIA), and antigen-induced arthritis (AIA) models will be presented. To achieve this, we will describe their method of induction and how to analyze RA clinical scores and pathology characteristics. Finally, we will briefly discuss the main features and drawbacks of all three models.
APA:
Grötsch, B., Bozec, A., & Schett, G. (2025). Models of Rheumatoid Arthritis. In Aymen I. Idris (Eds.), Bone Research Protocols. (pp. 345-357). New York, NY: Humana Press Inc..
MLA:
Grötsch, Bettina, Aline Bozec, and Georg Schett. "Models of Rheumatoid Arthritis." Bone Research Protocols. Ed. Aymen I. Idris, New York, NY: Humana Press Inc., 2025. 345-357.
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