Intravascular Lipoleiomyoma With Expansion Into the Right Atrium and Subsequent Debulking Surgery
Traub A, Vorwerk J, Morf J, Baumgarten N, Agaimy A, Horn M, Ensminger S, Barkhausen J, Khandanpour C, von Bubnoff N, Kebenko M (2025)
Publication Language: English
Publication Type: Journal article
Publication year: 2025
Journal
Book Volume: 30
Article Number: 103764
Journal Issue: 15
DOI: 10.1016/j.jaccas.2025.103764
Abstract
Backround: Lipoleiomyomas are rare, benign tumors combining smooth muscle and adipose tissue, most commonly found in the uterus. Case Summary: A 61-year-old woman with a history of surgical treatment of uterine leiomyoma presented with syncopal episodes. Echocardiography revealed masses in the right atrium that led to urgent partial resection of a 10-cm tumor originating from the iliac veins. Three years later, recurrence was detected, extending from the iliac vessels to the atrium. This required complex thoracoabdominal surgery with an R1/2 resection, indicating a high likelihood of tumor recurrence. Pathologic examination confirmed an angioleiomyomatous tumor. Given its hormone receptor positivity, adjunctive letrozole therapy was initiated. Follow-up scans showed tumor regression, and the patient remains asymptomatic. Discussion: For hormone receptor–positive cases, aromatase inhibitors may offer a viable option for managing recurrent tumors when complete resection is unachievable. Take-Home Message: This case underscores the importance of a multidisciplinary approach for intravenous leiomyomas with cardiac involvement.
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Germany (DE)How to cite
APA:
Traub, A., Vorwerk, J., Morf, J., Baumgarten, N., Agaimy, A., Horn, M.,... Kebenko, M. (2025). Intravascular Lipoleiomyoma With Expansion Into the Right Atrium and Subsequent Debulking Surgery. JACC: Case Reports, 30(15). https://doi.org/10.1016/j.jaccas.2025.103764
MLA:
Traub, Anna, et al. "Intravascular Lipoleiomyoma With Expansion Into the Right Atrium and Subsequent Debulking Surgery." JACC: Case Reports 30.15 (2025).
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