Roy-Chowdhury EAM, Angerer M, Schlötzer-Schrehardt U, Tourtas T, Kruse F, Weller J (2025)
Publication Type: Journal article
Publication year: 2025
Book Volume: 44
Pages Range: 740-749
Journal Issue: 6
DOI: 10.1097/ICO.0000000000003603
Purpose:To analyze the feasibility and outcome of Descemet membrane endothelial keratoplasty (DMEK) for treatment of endothelial failure in primary angle closure suspect (PACS) eyes.Methods:Retrospective, single-center case series of eyes treated by DMEK for endothelial failure caused by PACS. Main study parameters were success rate of DMEK, best-corrected visual acuity, anterior chamber depth, central corneal thickness, and endothelial cell density. Mean follow-up time was 16 ± 13 months.Results:Ten eyes of 9 patients receiving DMEK for the treatment of corneal endothelial failure because of PACS were included. Except for 2 eyes that had undergone cataract surgery, none of the eyes had previous ocular surgery. DMEK combined with cataract surgery was performed in 5 eyes, DMEK alone with second-step cataract surgery in 2 eyes. The eyes with corneal edema after cataract surgery received DMEK only. DMEK surgery was successful in nine out of 10 eyes, 1 patient required repeat DMEK because of primary graft failure. In the group of phakic eyes, mean preoperative internal anterior chamber depth was 1.74 ± 0.18 mm. In eyes with corneal edema, central corneal thickness was 849 ± 205 m before DMEK surgery, and 517 ± 24 m at the final postoperative visit (P = 0.002).Conclusions:DMEK is a feasible option in eyes with endothelial failure because of primary angle closure. In case of advanced corneal edema, a second-step procedure (first DMEK, second cataract surgery) is a possible approach if visibility of the lens is too poor for simultaneous cataract surgery.
APA:
Roy-Chowdhury, E.A.M., Angerer, M., Schlötzer-Schrehardt, U., Tourtas, T., Kruse, F., & Weller, J. (2025). Descemet Membrane Endothelial Keratoplasty for Endothelial Failure in Primary Angle Closure Suspects. Cornea, 44(6), 740-749. https://doi.org/10.1097/ICO.0000000000003603
MLA:
Roy-Chowdhury, Eva Anna Maria, et al. "Descemet Membrane Endothelial Keratoplasty for Endothelial Failure in Primary Angle Closure Suspects." Cornea 44.6 (2025): 740-749.
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