HERON: High-Efficiency Real-Time mOtion quantification and re-acquisitioN for Fetal diffusion MRI

Aviles Verdera J, Bortolazzi A, Silva SN, Payette K, Clair KS, McElroy S, Malik S, Hajnal J, Tomi-Tricot R, Hutter J (2025)

Publication Type: Journal article

Publication year: 2025

Journal

IEEE Transactions on Medical Imaging Institute of Electrical and Electronics Engineers (IEEE)

DOI: 10.1109/TMI.2025.3569853

Abstract

Fetal diffusion MRI (dMRI) provides fascinating and clinically crucial insights into the microstructure of the human brain during development, but is highly sensitive to motion artifacts of fetal movement and maternal breathing, which impact data quality and limit diagnostic accuracy. This study introduces HERON, a robust, real-time, automatic pipeline designed to enhance fetal brain dMRI by performing motion assessment and re-acquisition. HERON leverages AI-driven brain localization, segmentation, and motion assessment on a clinical 0.55T scanner to automatically plan, quality check, and reacquire motion-affected dMRI volumes. Remaining inter-volume motion is corrected during post-processing. Tested in 20 cases, the pipeline effectively improved image quality, reduced intra- and inter-volume motion, and enabled more reliable quantitative analysis even in challenging cases. Excellent agreement with human observers (specificity 97%, sensitivity 92%) was shown and the mean Apparent Diffusion Coefficient and Intravoxel Incoherent Motion dropped in the majority of cases after correction. Improving fetal dMRI through an automatic AI-driven pipeline enables higher diagnostic quality and thus potentially wider use in both research and clinical applications.

Authors with CRIS profile

Jordina Aviles Verdera Institute of Radiology Jana Hutter Professur für Smart Imaging and Data Profiling (Heisenberg-Professur)

Involved external institutions

King’s College London GB United Kingdom (GB) Siemens GB United Kingdom (GB)

How to cite

APA:

Aviles Verdera, J., Bortolazzi, A., Silva, S.N., Payette, K., Clair, K.S., McElroy, S.,... Hutter, J. (2025). HERON: High-Efficiency Real-Time mOtion quantification and re-acquisitioN for Fetal diffusion MRI. IEEE Transactions on Medical Imaging. https://doi.org/10.1109/TMI.2025.3569853

MLA:

Aviles Verdera, Jordina, et al. "HERON: High-Efficiency Real-Time mOtion quantification and re-acquisitioN for Fetal diffusion MRI." IEEE Transactions on Medical Imaging (2025).

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