Hybrid supraparticles for combined MPI and magnetic hyperthermia
Müssig S, Ackers J, Aderhold E, Heinlein M, Kluwe B, Wei H, Mandel K, Bakenecker AC (2025)
Publication Language: English
Publication Type: Journal article
Publication year: 2025
Journal
Book Volume: 11
Article Number: 2503034
Journal Issue: 1 Suppl 1
DOI: 10.18416/IJMPI.2025.2503034
Abstract
Combining magnetic particle imaging (MPI) with magnetic hyperthermia in a single location opens new effective theranostic applications, e.g. in targeted cancer therapy. We present the utilization of hybrid supraparticles containing two nanoparticle species to create particles with optimized magnetic properties for both technologies. For this, ferromagnetic particles, which are known for their good performance for hyperthermia are combined with superparamagnetic particles, which are very well suitable for MPI. The supraparticles are characterized regarding their MPS spectra and heating power during magnetic hyperthermia. Additionally, first experiments demonstrate the feasibility of the approach also for imaging. The results represent a proof-of-concept for the supraparticle approach, which will facilitate the optimization of particle properties for both technnologies at the same time.
Authors with CRIS profile
Stephan Müssig
Professur für Anorganische Chemie
Markus Heinlein
Professur für Anorganische Chemie
Karl Mandel
Professur für Anorganische Chemie
Involved external institutions
Germany (DE)How to cite
APA:
Müssig, S., Ackers, J., Aderhold, E., Heinlein, M., Kluwe, B., Wei, H.,... Bakenecker, A.C. (2025). Hybrid supraparticles for combined MPI and magnetic hyperthermia. International Journal of Magnetic Particle Imaging, 11(1 Suppl 1). https://doi.org/10.18416/IJMPI.2025.2503034
MLA:
Müssig, Stephan, et al. "Hybrid supraparticles for combined MPI and magnetic hyperthermia." International Journal of Magnetic Particle Imaging 11.1 Suppl 1 (2025).
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