Role of microbiome-gut-brain axis in autism spectrum disorder

Chand J, Patel N, Khare P (2025)

Publication Type: Authored book

Publication year: 2025

Publisher: Elsevier

ISBN: 9780443216800

DOI: 10.1016/B978-0-443-21680-0.00006-7

Abstract

Autism spectrum disorder (ASD) is a neurological disorder that affects an individual's communication, behavior, and social interaction. Promising treatments specifically targeting the underlying neurophysiology of ASD are currently being developed. In this chapter, we review the pathophysiology and current pharmacological treatment options, along with the detailed role of the gut-brain axis in the ASD phenotype. The review integrates recent findings on the gut microbiota and ASD, addressing potential therapeutic interventions to restore a healthy balance of gut microbiome composition that can improve autism-associated symptoms.

Authors with CRIS profile

Neha Patel Lehrstuhl für Anorganische und Metallorganische Chemie

Involved external institutions

Birla Institute of Technology and Science (BITS) IN India (IN)

How to cite

APA:

Chand, J., Patel, N., & Khare, P. (2025). Role of microbiome-gut-brain axis in autism spectrum disorder. Elsevier.

MLA:

Chand, Jagdish, Neha Patel, and Pragyanshu Khare. Role of microbiome-gut-brain axis in autism spectrum disorder. Elsevier, 2025.

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