Antimicrobial photodynamic inactivation of Pseudomonas aeruginosa persister cells and biofilms

Mahmoud M, Richter P, Arnold P, Lebert M, Burkovski A (2025)

Publication Language: English

Publication Type: Journal article

Publication year: 2025

Journal

Photodiagnosis and Photodynamic Therapy Elsevier

Book Volume: 51

Article Number: 104456

DOI: 10.1016/j.pdpdt.2024.104456

Abstract

Pseudomonas aeruginosa is a hard-to-treat human pathogen for which new antimicrobial agents are urgently needed. P. aeruginosa is known for forming biofilms, a complex aggregate of bacteria embedded in a self-generated protective matrix that enhance its resistance to antibiotics and the immune system. Within the biofilm, persister cells, sub-populations of slow-growing or growth-arrested cells, are associated with recalcitrance of infections and antibiotic treatment failure. Here, we investigate the influence of the anionic photosensitiser chlorophyllin (CHL)¹

Authors with CRIS profile

Mona Mahmoud Professur für Mikrobiologie Peter Richter Lehrstuhl für Zellbiologie Philipp Arnold Lehrstuhl für Funktionelle und Klinische Anatomie Michael Lebert Lehrstuhl für Zellbiologie Andreas Burkovski Professur für Mikrobiologie

How to cite

APA:

Mahmoud, M., Richter, P., Arnold, P., Lebert, M., & Burkovski, A. (2025). Antimicrobial photodynamic inactivation of Pseudomonas aeruginosa persister cells and biofilms. Photodiagnosis and Photodynamic Therapy, 51. https://doi.org/10.1016/j.pdpdt.2024.104456

MLA:

Mahmoud, Mona, et al. "Antimicrobial photodynamic inactivation of Pseudomonas aeruginosa persister cells and biofilms." Photodiagnosis and Photodynamic Therapy 51 (2025).

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