Functional Specialization of Dendritic Cell Subsets

Heger L, Amon L, Lehmann C, Baranska A, Heidkamp G, Dudziak D (2022)

Publication Type: Authored book

Publication year: 2022

Publisher: Elsevier

ISBN: 9780128216248

DOI: 10.1016/B978-0-12-821618-7.00257-1

Abstract

Dendritic cells (DCs) are sentinels of the immune system. Under inflammatory conditions, DCs undergo various phenotypical changes, including DC migration, upregulation of co-stimulatory and activating molecules, secretion of cytokines, but also the processing of the engulfed antigens. The DC presents short antigenic peptides on the DC surface as peptide MHC class I or MHC class II complexes to CD8+ or CD4+ T cells, respectively. This article will provide a detailed overview on the antigen processing machineries and specialized functions of the increasing variety of DC subsets in mice and men.

Authors with CRIS profile

Lukas Heger Department of Dermatology Lukas Amon Department of Dermatology Christian Lehmann Department of Dermatology Diana Dudziak Professur für die Biologie Dendritischer Zellen

Involved external institutions

Roche Deutschland Holding GmbH DE Germany (DE) Miltenyi Biotec GmbH DE Germany (DE)

How to cite

APA:

Heger, L., Amon, L., Lehmann, C., Baranska, A., Heidkamp, G., & Dudziak, D. (2022). Functional Specialization of Dendritic Cell Subsets. Elsevier.

MLA:

Heger, Lukas, et al. Functional Specialization of Dendritic Cell Subsets. Elsevier, 2022.

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