Pancreas transplantation as rescue therapy in a patient with type 1 diabetes and concurrent subcutaneous insulin resistance

Füermann F, Heller KM, Pavel ME, Herbst L, Grützmann R, Schiffer M (2024)

Publication Language: English

Publication Type: Journal article, Medical case study

Publication year: 2024

Journal

American Journal of Transplantation Wiley

Book Volume: 24

Pages Range: 2125-2128

Journal Issue: 11

DOI: 10.1016/j.ajt.2024.07.030

Abstract

Patients with type 1 diabetes and concurrent subcutaneous insulin resistance present unique diagnostic and therapeutic challenges for clinicians. The standard therapeutic approach is the administration of intravenous insulin. Pancreatic transplantation should be considered at an appropriate time, particularly in the event of life-threatening ketoacidosis, hyperglycemia, hypoglycemia, catheter-associated thrombosis, and infections. We present the case of a 24-year-old woman with type 1 diabetes since early childhood and increasingly uncontrollable subcutaneous and intramuscular insulin resistance. Furthermore, we present the diagnostic pathway and therapeutic interventions performed, culminating in pancreatic transplantation as a curative approach. Immediate graft function resulted in optimal glycemic control.

Authors with CRIS profile

Florian Füermann Department of Medicine 4 – Nephrology and Hypertension Marianne Ellen Pavel Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Larissa Herbst Department of Medicine 4 – Nephrology and Hypertension Robert Grützmann Lehrstuhl für Allgemein- und Viszeralchirurgie Mario Schiffer Lehrstuhl für Innere Medizin IV

How to cite

APA:

Füermann, F., Heller, K.M., Pavel, M.E., Herbst, L., Grützmann, R., & Schiffer, M. (2024). Pancreas transplantation as rescue therapy in a patient with type 1 diabetes and concurrent subcutaneous insulin resistance. American Journal of Transplantation, 24(11), 2125-2128. https://doi.org/10.1016/j.ajt.2024.07.030

MLA:

Füermann, Florian, et al. "Pancreas transplantation as rescue therapy in a patient with type 1 diabetes and concurrent subcutaneous insulin resistance." American Journal of Transplantation 24.11 (2024): 2125-2128.

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