Bagci C, Bastan FE, Nawaz Q, Hurle K, de Ligny D, Boccaccini AR (2024)
Publication Language: English
Publication Type: Journal article
Publication year: 2024
Book Volume: 50
Pages Range: 50200-50212
Journal Issue: 23, Part A
DOI: 10.1016/j.ceramint.2024.09.367
In this study, silicon nitride (Si3N4, SN) particles (10–30 wt%) were introduced into 45S5 bioactive glass (BG), and the impact of the incorporation on thermal and physicochemical features of the composite was analyzed. SN inclusion shifted the crystallization temperature of BG to higher temperatures, thus, the viscous flow of the glassy phase enhanced the sintering-ability and eventually reduced the sintering temperature from 1050 °C to 900 °C. XRD results revealed that increased SN fractions sustained higher amorphous content while decreasing the fraction of the main BG crystallization phase (combeite). BG + SN composites were cytocompatible with MG-63 cells. A higher number of cells was visualized on the BG + SN pellets, yet no statistically significant viability difference was determined between the BG + SN and BG samples. SN addition also endowed antibacterial activity to the BG + SN composites against S. aureus and E. coli pathogens, revealing that SN addition to BG is an alternative approach to developing biocompatible, bioactive, and antibacterial materials.
APA:
Bagci, C., Bastan, F.E., Nawaz, Q., Hurle, K., de Ligny, D., & Boccaccini, A.R. (2024). Effects of silicon nitride (Si3N4) incorporation on physicochemical, bioactivity and antibacterial properties of 45S5 bioactive glass. Ceramics International, 50(23, Part A), 50200-50212. https://doi.org/10.1016/j.ceramint.2024.09.367
MLA:
Bagci, Cengiz, et al. "Effects of silicon nitride (Si3N4) incorporation on physicochemical, bioactivity and antibacterial properties of 45S5 bioactive glass." Ceramics International 50.23, Part A (2024): 50200-50212.
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