Therapeutic Drug Monitoring of Long-Acting Rilpivirine and Cabotegravir for Treatment of HIV-1 Infection - A Case Series of Five Patients With One Virologic Failure After Development of Two-Class Resistance
Gerstenberg J, Klinker H, Baier M, Von Braun A, Seybold U, Helbig C, Däumer M, Korn K, Stephan C, Schleenvoigt BT (2024)
Publication Type: Journal article
Publication year: 2024
Journal
Book Volume: 11
Article Number: ofae480
Journal Issue: 9
DOI: 10.1093/ofid/ofae480
Abstract
Virologic failure of long-acting rilpivirine/cabotegravir is rare but may result in severely limited treatment options. Known risk factors cannot predict all cases. Therapeutic drug monitoring (TDM) may help identify patients at risk, but reliable thresholds are missing. We report retrospective TDM in a cohort of 5 patients, including 1 virological failure.
Authors with CRIS profile
Involved external institutions
Eberhard Karls Universität Tübingen
Germany (DE)
Julius-Maximilians-Universität Würzburg
Germany (DE)
Universitätsklinikum Jena
Germany (DE)
Universitätsklinikum Leipzig
Germany (DE)
Klinikum der Universität München
Germany (DE)
Institut für Immunologie und Genetik
Germany (DE)
Universitätsklinikum Frankfurt am Main (KGU)
Germany (DE)
Germany (DE)
Julius-Maximilians-Universität Würzburg
Germany (DE)
Universitätsklinikum Jena
Germany (DE)
Universitätsklinikum Leipzig
Germany (DE)
Klinikum der Universität München
Germany (DE)
Institut für Immunologie und Genetik
Germany (DE)
Universitätsklinikum Frankfurt am Main (KGU)
Germany (DE)
How to cite
APA:
Gerstenberg, J., Klinker, H., Baier, M., Von Braun, A., Seybold, U., Helbig, C.,... Schleenvoigt, B.T. (2024). Therapeutic Drug Monitoring of Long-Acting Rilpivirine and Cabotegravir for Treatment of HIV-1 Infection - A Case Series of Five Patients With One Virologic Failure After Development of Two-Class Resistance. Open Forum Infectious Diseases, 11(9). https://doi.org/10.1093/ofid/ofae480
MLA:
Gerstenberg, Jacob, et al. "Therapeutic Drug Monitoring of Long-Acting Rilpivirine and Cabotegravir for Treatment of HIV-1 Infection - A Case Series of Five Patients With One Virologic Failure After Development of Two-Class Resistance." Open Forum Infectious Diseases 11.9 (2024).
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