Cotton wool-like ion-doped bioactive glass nanofibers: investigation of Zn and Cu combined effect

Ünalan I, Rimoli IH, Mutlu N, Michálek M, Abraham GA, Liverani L, Boccaccini AR (2024)

Publication Language: English

Publication Type: Journal article

Publication year: 2024

Journal

Biomedical Materials Institute of Physics

Book Volume: 19

Article Number: 065001

Journal Issue: 6

DOI: 10.1088/1748-605X/ad7084

Abstract

Electrospinning is a versatile and straightforward technique to produce nanofibrous mats with different morphologies. In addition, by optimizing the solution, processing, and environmental parameters, three-dimensional (3D) nanofibrous scaffolds can also be created using this method. In this work, the preparation and characterization of bioactive glass (BG) scaffolds based on the SiO2-CaO sol-gel system, a biomaterial with a highly reactive surface, is reported. The electrospinning technique was combined with sol-gel methods to obtain nanofibrous 3D cotton wool-like scaffolds. The addition of zinc and copper ions to the silica-calcia system was examined, and the influence of these ions on the material properties and characteristics was investigated by various characterization techniques, from morphological and chemical properties to antibacterial and wound closure capability, cell viability and ion release. Our findings show that the cotton wool-like ion-doped nanofibers are promising for wound healing applications.

Authors with CRIS profile

Irem Ünalan Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Liliana Liverani Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Additional Organisation(s)

FAU Forschungszentrum Neue Wirkstoffe (FAU NeW)

Involved external institutions

Trenčianska univerzita Alexandra Dubčeka v Trenčíne SK Slovakia (SK) National University of Mar del Plata / Universidad Nacional de Mar del Plata (UNMdP) AR Argentina (AR)

How to cite

APA:

Ünalan, I., Rimoli, I.H., Mutlu, N., Michálek, M., Abraham, G.A., Liverani, L., & Boccaccini, A.R. (2024). Cotton wool-like ion-doped bioactive glass nanofibers: investigation of Zn and Cu combined effect. Biomedical Materials, 19(6). https://doi.org/10.1088/1748-605X/ad7084

MLA:

Ünalan, Irem, et al. "Cotton wool-like ion-doped bioactive glass nanofibers: investigation of Zn and Cu combined effect." Biomedical Materials 19.6 (2024).

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