Multifunctional tunable Cu2O and CuInS2 quantum dots on TiO2 nanotubes for efficient chemical oxidation of cholesterol and ibuprofen

Khaliq N, Ali G, Rasheed MA, Khan M, Xie Y, Schmuki P, Cho SO, Karim S (2024)

Publication Type: Journal article

Publication year: 2024

Journal

Nanoscale Royal Society of Chemistry

DOI: 10.1039/d4nr00422a

Abstract

In this study, a CuInS2/Cu2O/TiO2 nanotube (TNT) heterojunction-based hybrid material is reported for the selective detection of cholesterol and ibuprofen. Anodic TNTs were co-decorated with Cu2O and CuInS2 quantum dots (QDs) using a modified chemical bath deposition (CBD) method. QDs help trigger the chemical oxidation of cholesterol by cathodically generating hydroxyl radicals (?OH). The small size of QDs can be used to tune the energy levels of electrode materials to the effective redox potential of redox species, resulting in highly improved sensing characteristics. Under optimal conditions, CuInS2/Cu2O/TNTs show the highest sensitivity (~12 530 µA mM-1 cm-2, i.e. up to 11-fold increase compared to pristine TNTs) for cholesterol detection with a low detection limit (0.013 µM) and a fast response time (1.3 s). The proposed biosensor was successfully employed for the detection of cholesterol in real blood samples. In addition, fast (4 s) and reliable detection of ibuprofen (with a sensitivity of ~1293 µA mM-1 cm-2) as a water contaminant was achieved using CuInS2/Cu2O/TNTs. The long-term stability and favourable reproducibility of CuInS2/Cu2O/TNTs illustrate a unique concept for the rational design of a stable and high-performance multi-purpose electrochemical sensor.

Authors with CRIS profile

Patrik Schmuki Lehrstuhl für Werkstoffwissenschaften (Korrosion und Oberflächentechnik) (LKO)

Involved external institutions

Pakistan Institute of Engineering & Applied Sciences (PIEAS) PK Pakistan (PK) Pakistan Institute of Nuclear Science and Technology PK Pakistan (PK) Wuhan University of Technology CN China (CN) Korea Advanced Institute of Science and Technology (KAIST) KR Korea, Republic of (KR)

How to cite

APA:

Khaliq, N., Ali, G., Rasheed, M.A., Khan, M., Xie, Y., Schmuki, P.,... Karim, S. (2024). Multifunctional tunable Cu2O and CuInS2 quantum dots on TiO2 nanotubes for efficient chemical oxidation of cholesterol and ibuprofen. Nanoscale. https://doi.org/10.1039/d4nr00422a

MLA:

Khaliq, Nilem, et al. "Multifunctional tunable Cu2O and CuInS2 quantum dots on TiO2 nanotubes for efficient chemical oxidation of cholesterol and ibuprofen." Nanoscale (2024).

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