Pöschke P, Gaß P, Krückel A, Keller K, Erber R, Hartmann A, Beckmann M, Emons J (2024)
Publication Type: Journal article
Publication year: 2024
Book Volume: 84
Pages Range: 470-476
Journal Issue: 5
DOI: 10.1055/a-2293-5700
Introduction The medical and surgical treatment of endometrial cancer (EC) is evolving toward a more patient-centered and personalized approach. The role of laparoscopic sentinel node biopsy (SNB) for early-stage EC is unclear, and very few data are available for atypical endometrial hyperplasia (AEH). The present study investigated the effectiveness of SNB combined with laparoscopic hysterectomy in patients with early-stage EC and AEH. Patients and Methods This was a retrospective, single-center cohort study for the period from January 2018 to December 2023. A total of 102 patients with atypical hyperplasia (n = 20) and early-stage EC (n = 82) findings on diagnostic curettage underwent pelvic sentinel node biopsy during the final operation. Results Eleven patients (55%) who had initially been diagnosed with AEH were found to have EC in the final pathology report. No lymph node metastases were detected in patients who had initially been diagnosed with AEH; a 3.6% rate of positive SNBs was found in patients with EC. Changes in tumor grade occurred in 31.3% of the patients and changes in FIGO stage in 33%. Bilateral sentinel node (SN) mapping was successful in 94.1% of the patients. The postoperative outcomes were comparable to those of routine clinical practice without SNB. Conclusions SNB can be safely offered to patients who have precursor lesions and early-stage EC without notably extending surgical times or increasing postoperative morbidity. This approach can be considered and is safe for patients diagnosed with AEH, but it appears to have a rather small impact on these patients.
APA:
Pöschke, P., Gaß, P., Krückel, A., Keller, K., Erber, R., Hartmann, A.,... Emons, J. (2024). Clinical and Surgical Evaluation of Sentinel Node Biopsy in Patients with Early-Stage Endometrial Cancer and Atypical Hyperplasia Klinische und chirurgische Evaluation der Sentinel-Lymphknoten- Biopsie in Patientinnen mit Endometriumkarzinom im Fr hstadium und atypischer Hyperplasie. Geburtshilfe und Frauenheilkunde, 84(5), 470-476. https://doi.org/10.1055/a-2293-5700
MLA:
Pöschke, Patrik, et al. "Clinical and Surgical Evaluation of Sentinel Node Biopsy in Patients with Early-Stage Endometrial Cancer and Atypical Hyperplasia Klinische und chirurgische Evaluation der Sentinel-Lymphknoten- Biopsie in Patientinnen mit Endometriumkarzinom im Fr hstadium und atypischer Hyperplasie." Geburtshilfe und Frauenheilkunde 84.5 (2024): 470-476.
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