12-Month Trajectories of Health-Related Quality of Life Following Hospitalization in German Cancer Centers—A Secondary Data Analysis

Eichler M, Hönig K, Bergelt C, Faller H, Maatouk I, Hornemann B, Stein B, Teufel M, Goerling U, Erim Y, Geiser F, Niecke A, Senf B, Weis J (2024)

Publication Type: Journal article

Publication year: 2024

Journal

Current Oncology Multimed Inc.

Book Volume: 31

Pages Range: 2376-2392

Journal Issue: 5

DOI: 10.3390/curroncol31050177

Abstract

Patient-reported outcomes (PROs) offer a diverse array of potential applications within medical research and clinical practice. In comparative research, they can serve as tools for delineating the trajectories of health-related quality of life (HRQoL) across various cancer types. We undertook a secondary data analysis of a cohort of 1498 hospitalized cancer patients from 13 German cancer centers. We assessed the Physical and Mental Component Scores (PCS and MCS) of the 12-Item Short-Form Health Survey at baseline (t0), 6 (t1), and 12 months (t2), using multivariable generalized linear regression models. At baseline, the mean PCS and MCS values for all cancer patients were 37.1 and 44.3 points, respectively. We observed a significant improvement in PCS at t2 and in MCS at t1. The most substantial and significant improvements were noted among patients with gynecological cancers. We found a number of significant differences between cancer types at baseline, t1, and t2, with skin cancer patients performing best across all time points and lung cancer patients performing the worst. MCS trajectories showed less pronounced changes and differences between cancer types. Comparative analyses of HRQoL scores across different cancer types may serve as a valuable tool for enhancing health literacy, both among the general public and among cancer patients themselves.

Authors with CRIS profile

Yesim Erim Professur für Psychosomatik und Psychotherapie

Involved external institutions

Universitätsklinikum Ulm DE Germany (DE) Paracelsus Medizinische Privatuniversität, Nürnberg DE Germany (DE) Universität Duisburg-Essen (UDE) DE Germany (DE) Berliner Institut für Gesundheitsforschung (BIH) DE Germany (DE) Universität zu Köln DE Germany (DE) Universitätsklinikum Frankfurt am Main (KGU) DE Germany (DE) Universitätsklinikum Freiburg DE Germany (DE) Universitätsklinikum Hamburg-Eppendorf (UKE) DE Germany (DE) Julius-Maximilians-Universität Würzburg DE Germany (DE) Universitätsklinikum Heidelberg DE Germany (DE) Universitätsklinikum Carl Gustav Carus Dresden DE Germany (DE) Universitätsklinikum Bonn DE Germany (DE)

How to cite

APA:

Eichler, M., Hönig, K., Bergelt, C., Faller, H., Maatouk, I., Hornemann, B.,... Weis, J. (2024). 12-Month Trajectories of Health-Related Quality of Life Following Hospitalization in German Cancer Centers—A Secondary Data Analysis. Current Oncology, 31(5), 2376-2392. https://doi.org/10.3390/curroncol31050177

MLA:

Eichler, Martin, et al. "12-Month Trajectories of Health-Related Quality of Life Following Hospitalization in German Cancer Centers—A Secondary Data Analysis." Current Oncology 31.5 (2024): 2376-2392.

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