In vivo measurement of the biomechanical properties of human skin with motion-corrected Brillouin microscopy
Romodina MN, Parmar A, Singh K (2024)
Publication Type: Journal article
Publication year: 2024
Journal
Book Volume: 15
Pages Range: 1777-1784
Journal Issue: 3
DOI: 10.1364/BOE.516032
Abstract
Biomechanical testing of human skin in vivo is important to study the aging process and pathological conditions such as skin cancer. Brillouin microscopy allows the all-optical, non-contact visualization of the mechanical properties of cells and tissues over space. Here, we use the combination of Brillouin microscopy and optical coherence tomography for motion-corrected, depth-resolved biomechanical testing of human skin in vivo. We obtained two peaks in the Brillouin spectra for the epidermis, the first at 7 GHz and the second near 9-10 GHz. The experimentally measured Brillouin frequency shift of the dermis is lower compared to the epidermis and is 6.8 GHz, indicating the lower stiffness of the dermis.
Involved external institutions
Germany (DE)How to cite
APA:
Romodina, M.N., Parmar, A., & Singh, K. (2024). In vivo measurement of the biomechanical properties of human skin with motion-corrected Brillouin microscopy. Biomedical Optics Express, 15(3), 1777-1784. https://dx.doi.org/10.1364/BOE.516032
MLA:
Romodina, Maria N., Asha Parmar, and Kanwarpal Singh. "In vivo measurement of the biomechanical properties of human skin with motion-corrected Brillouin microscopy." Biomedical Optics Express 15.3 (2024): 1777-1784.
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