Innate immune response to Anaplasma phagocytophilum contributes to hepatic injury

Scorpio DG, Von Loewenich FD, Goebel H, Bogdan C, Dumler JS (2006)

Publication Type: Journal article

Publication year: 2006

Journal

Clinical and Vaccine Immunology American Society for Microbiology

Book Volume: 13

Pages Range: 806-809

Journal Issue: 7

DOI: 10.1128/CVI.00092-06

Abstract

In mice, Anaplasma phagocytophilum control is independent of phagocyte oxidase (phox), inducible NO synthase (NOS2), tumor necrosis factor (TNF), and MyD88 Toll-like receptor signaling. We show that despite evasion of these host responses, phox, NOS2, TNF, and MyD88 are activated and contribute to inflammation and hepatic injury more than A. phagocytophilum itself. Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Authors with CRIS profile

Christian Bogdan

Involved external institutions

Albert-Ludwigs-Universität Freiburg DE Germany (DE) Johns Hopkins University (JHU) US United States (USA) (US) Universitätsklinikum Köln DE Germany (DE)

How to cite

APA:

Scorpio, D.G., Von Loewenich, F.D., Goebel, H., Bogdan, C., & Dumler, J.S. (2006). Innate immune response to Anaplasma phagocytophilum contributes to hepatic injury. Clinical and Vaccine Immunology, 13(7), 806-809. https://doi.org/10.1128/CVI.00092-06

MLA:

Scorpio, Diana G., et al. "Innate immune response to Anaplasma phagocytophilum contributes to hepatic injury." Clinical and Vaccine Immunology 13.7 (2006): 806-809.

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