ILAE neuroimaging task force highlight: Subcortical laminar heterotopia

Kasper BS, Archer J, Bernhardt BC, Caciagli L, Cendes F, Chinvarun Y, Concha L, Federico P, Gaillard W, Kobayashi E, Ogbole G, Vaudano A, Wang I, Wang S, Winston G, Rampp S (2024)

Publication Type: Journal article

Publication year: 2024

Journal

Epileptic Disorders John Libbey Eurotext

DOI: 10.1002/epd2.20206

Abstract

The ILAE Neuroimaging Task Force publishes educational case reports that highlight basic aspects of neuroimaging in epilepsy consistent with the ILAE's educational mission. Subcortical laminar heterotopia, also known as subcortical band heterotopia (SBH) or “double cortex,” is an intriguing and rare congenital malformation of cortical development. SBH lesions are part of a continuum best designated as agyria-pachygyria-band-spectrum. The malformation is associated with epilepsy that is often refractory, as well as variable degrees of developmental delay. Moreover, in an increasing proportion of cases, a distinct molecular-genetic background can be found. Diagnosing SBH can be a major challenge for many reasons, including more subtle lesions, and “non-classic” or unusual MRI-appearances. By presenting an illustrative case, we address the challenges and needs of diagnosing and treating SBH patients in epilepsy, especially the value of high-resolution imaging and specialized MRI-protocols.

Authors with CRIS profile

Burkhard Kasper Lehrstuhl für Neurologie Stefan Rampp Department of Neurosurgery

Additional Organisation(s)

Sonderforschungsbereich 1540: Erforschung der Mechanik des Gehirns (EBM): Verständnis, Engineering und Nutzung mechanischer Eigenschaften und Signale in der Entwicklung, Physiologie und Pathologie des zentralen Nervensystems FAU Profilzentrum Licht.Materie.Quantentechnologien (FAU LMQ)

Involved external institutions

Montreal Neurological Institute and Hospital (MNI, The Neuro) CA Canada (CA) Queen's University CA Canada (CA) University of Ibadan NG Nigeria (NG) National Autonomous University of Mexico / Universidad Nacional Autónoma de México (UNAM) MX Mexico (MX) The University of Melbourne AU Australia (AU) Cleveland Clinic US United States (USA) (US) George Washington University (GWU) US United States (USA) (US) Universidade Estadual de Campinas (UNICAMP) / University of Campinas BR Brazil (BR) McGill University CA Canada (CA) University of Calgary CA Canada (CA) Università degli Studi di Modena e Reggio Emilia (UNIMORE) IT Italy (IT) Inselspital, Universitätsspital Bern CH Switzerland (CH) Phramongkutklao Hospital / โรงพยาบาลพระมงกุฎเกล้า TH Thailand (TH) Zhejiang University CN China (CN)

How to cite

APA:

Kasper, B.S., Archer, J., Bernhardt, B.C., Caciagli, L., Cendes, F., Chinvarun, Y.,... Rampp, S. (2024). ILAE neuroimaging task force highlight: Subcortical laminar heterotopia. Epileptic Disorders. https://dx.doi.org/10.1002/epd2.20206

MLA:

Kasper, Burkhard S., et al. "ILAE neuroimaging task force highlight: Subcortical laminar heterotopia." Epileptic Disorders (2024).

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