Emergence of novel ST1299 vanA lineages as possible cause for the striking rise of vancomycin resistance among invasive strains of Enterococcus faecium at a German university hospital

Valenza G, Eisenberger D, Voigtländer S, Alsalameh R, Gerlach R, Koch S, Kunz B, Held J, Bogdan C (2023)

Publication Type: Journal article

Publication year: 2023

Journal

Microbiology Spectrum American Society for Microbiology (ASM)

Book Volume: 11

Pages Range: e0296223-

Journal Issue: 6

DOI: 10.1128/spectrum.02962-23

Abstract

IMPORTANCE: The proportion of VREfm among all Enterococcus faecium isolated from blood cultures in German hospitals has increased in the period 2015-2020 from 11.9% to 22.3% with a country-wide spread of the clonal lineage ST117/CT71 vanB. In this study, we provided useful information about the genetic diversity of invasive strains of E. faecium. Moreover, our findings confirm the nosocomial spread of novel ST1299 vanA lineages, which recently had a rapid expansion in Austria and the south-eastern part of Germany.

Authors with CRIS profile

Giuseppe Valenza Institute of Microbiology – Clinical Microbiology, Immunology and Hygiene Roman Gerlach Institute of Microbiology – Clinical Microbiology, Immunology and Hygiene Sonja Koch Department of Molecular Pneumology Bernd Kunz Institute of Microbiology – Clinical Microbiology, Immunology and Hygiene Jürgen Held Institute of Microbiology – Clinical Microbiology, Immunology and Hygiene Christian Bogdan Lehrstuhl für Mikrobiologie und Infektionsimmunologie

Involved external institutions

Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit (LGL) DE Germany (DE)

How to cite

APA:

Valenza, G., Eisenberger, D., Voigtländer, S., Alsalameh, R., Gerlach, R., Koch, S.,... Bogdan, C. (2023). Emergence of novel ST1299 vanA lineages as possible cause for the striking rise of vancomycin resistance among invasive strains of Enterococcus faecium at a German university hospital. Microbiology Spectrum, 11(6), e0296223-. https://doi.org/10.1128/spectrum.02962-23

MLA:

Valenza, Giuseppe, et al. "Emergence of novel ST1299 vanA lineages as possible cause for the striking rise of vancomycin resistance among invasive strains of Enterococcus faecium at a German university hospital." Microbiology Spectrum 11.6 (2023): e0296223-.

BibTeX: Download