Atherosclerotic renovascular disease: a clinical practice document by the European Renal Best Practice (ERBP) board of the European Renal Association (ERA) and the Working Group Hypertension and the Kidney of the European Society of Hypertension (ESH)

Sarafidis PA, Theodorakopoulou M, Ortiz A, Fernandez-Fernandez B, Nistor I, Schmieder R, Arici M, Saratzis A, Van Der Niepen P, Halimi JM, Kreutz R, Januszewicz A, Persu A, Cozzolino M (2023)

Publication Type: Journal article

Publication year: 2023

Journal

Nephrology Dialysis Transplantation Oxford University Press (OUP): Policy B

Book Volume: 38

Pages Range: 2835-2850

Journal Issue: 12

DOI: 10.1093/ndt/gfad095

Abstract

Atherosclerotic renovascular disease (ARVD) is the most common type of renal artery stenosis. It represents a common health problem with clinical presentations relevant to many medical specialties and carries a high risk for future cardiovascular and renal events, as well as overall mortality. The available evidence regarding the management of ARVD is conflicting. Randomized controlled trials failed to demonstrate superiority of percutaneous transluminal renal artery angioplasty (PTRA) with or without stenting in addition to standard medical therapy compared with medical therapy alone in lowering blood pressure levels or preventing adverse renal and cardiovascular outcomes in patients with ARVD, but they carried several limitations and met important criticism. Observational studies showed that PTRA is associated with future cardiorenal benefits in patients presenting with high-risk ARVD phenotypes (i.e. flash pulmonary oedema, resistant hypertension or rapid loss of kidney function). This clinical practice document, prepared by experts from the European Renal Best Practice (ERBP) board of the European Renal Association (ERA) and from the Working Group on Hypertension and the Kidney of the European Society of Hypertension (ESH), summarizes current knowledge in epidemiology, pathophysiology and diagnostic assessment of ARVD and presents, following a systematic literature review, key evidence relevant to treatment, with an aim to support clinicians in decision making and everyday management of patients with this condition.

Authors with CRIS profile

Roland Schmieder Professur für Innere Medizin (Nephrologie)

Involved external institutions

Università degli studi di Milano IT Italy (IT) Aristotle University of Thessaloniki GR Greece (GR) Hospital Universitario Fundación Jiménez Díaz ES Spain (ES) Institute of Cardiology in Warsaw PL Poland (PL) Berliner Institut für Gesundheitsforschung (BIH) DE Germany (DE) Hacettepe University TR Turkey (TR) Universitair Ziekenhuis Brussel BE Belgium (BE) Cliniques universitaires Saint-Luc (CHU St-Luc) BE Belgium (BE) Grigore T. Popa University of Medicine and Pharmacy / Universitatea de Medicină și Farmacie "Grigore T. Popa" (UMF Iași) RO Romania (RO) University Hospitals of Leicester NHS Trust GB United Kingdom (GB) Centre Hospitalier Régional Universitaire de Tours FR France (FR)

How to cite

APA:

Sarafidis, P.A., Theodorakopoulou, M., Ortiz, A., Fernandez-Fernandez, B., Nistor, I., Schmieder, R.,... Cozzolino, M. (2023). Atherosclerotic renovascular disease: a clinical practice document by the European Renal Best Practice (ERBP) board of the European Renal Association (ERA) and the Working Group Hypertension and the Kidney of the European Society of Hypertension (ESH). Nephrology Dialysis Transplantation, 38(12), 2835-2850. https://dx.doi.org/10.1093/ndt/gfad095

MLA:

Sarafidis, Pantelis A., et al. "Atherosclerotic renovascular disease: a clinical practice document by the European Renal Best Practice (ERBP) board of the European Renal Association (ERA) and the Working Group Hypertension and the Kidney of the European Society of Hypertension (ESH)." Nephrology Dialysis Transplantation 38.12 (2023): 2835-2850.

BibTeX: Download