Endodontic Tissue Regeneration: A Review for Tissue Engineers and Dentists

Astudillo-Ortiz E, Babo PS, Sunde PT, Galler KM, Gomez-Florit M, Gomes ME (2023)

Publication Type: Journal article, Review article

Publication year: 2023

Journal

Tissue Engineering - Part B: Reviews

Book Volume: 29

Pages Range: 491-513

Journal Issue: 5

DOI: 10.1089/ten.teb.2022.0211

Abstract

The paradigm shift in the endodontic field from replacement toward regenerative therapies has witnessed the ever-growing research in tissue engineering and regenerative medicine targeting pulp-dentin complex in the past few years. Abundant literature on the subject that has been produced, however, is scattered over diverse areas of knowledge. Moreover, the terminology and concepts are not always consensual, reflecting the range of research fields addressing this subject, from endodontics to biology, genetics, and engineering, among others. This fact triggered some misinterpretations, mainly when the denominations of different approaches were used as synonyms. The evaluation of results is not precise, leading to biased conjectures. Therefore, this literature review aims to conceptualize the commonly used terminology, summarize the main research areas on pulp regeneration, identify future trends, and ultimately clarify whether we are really on the edge of a paradigm shift in contemporary endodontics toward pulp regeneration.

Authors with CRIS profile

Kerstin Martina Galler Lehrstuhl für Zahn-,Mund- und Kieferheilkunde, insbesondere Zahnerhaltung, Parodontologie und Kinderzahnheilkunde

Involved external institutions

Health Research Institute of the Balearic Islands / Instituto de Investigación Sanitaria Illes Balears (IdISBa) ES Spain (ES) Universidade do Minho PT Portugal (PT) University of Oslo NO Norway (NO)

How to cite

APA:

Astudillo-Ortiz, E., Babo, P.S., Sunde, P.T., Galler, K.M., Gomez-Florit, M., & Gomes, M.E. (2023). Endodontic Tissue Regeneration: A Review for Tissue Engineers and Dentists. Tissue Engineering - Part B: Reviews, 29(5), 491-513. https://dx.doi.org/10.1089/ten.teb.2022.0211

MLA:

Astudillo-Ortiz, Esteban, et al. "Endodontic Tissue Regeneration: A Review for Tissue Engineers and Dentists." Tissue Engineering - Part B: Reviews 29.5 (2023): 491-513.

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