S3 guideline „actinic keratosis and cutaneous squamous cell carcinoma“ – update 2023, part 2: epidemiology and etiology, diagnostics, surgical and systemic treatment of cutaneous squamous cell carcinoma (cSCC), surveillance and prevention

Leiter U, Heppt M, Steeb T, Alter M, Amaral T, Bauer A, Bechara FG, Becker JC, Breitbart EW, Breuninger H, Diepgen T, Dirschka T, Eigentler T, ElGammal AK, Felcht M, Flaig MJ, Follmann M, Fritz K, Grabbe S, Greinert R, Gutzmer R, Hauschild A, Hillen U, Ihrler S, John SM, Kofler L, Koelbl O, Krause-Bergmann A, Kraywinkel K, Krohn S, Langer T, Loquai C, Löser CR, Mohr P, Nashan D, Nothacker M, Pfannenberg C, Salavastru C, Schmitz L, Stockfleth E, Szeimies RM, Ulrich C, Voelter-Mahlknecht S, Vordermark D, Weichenthal M, Welzel J, Wermker K, Wiegand S, Garbe C, Berking C (2023)

Publication Type: Journal article

Publication year: 2023

Journal

Book Volume: 21

Pages Range: 1422-1433

Journal Issue: 11

DOI: 10.1111/ddg.15256

Abstract

Actinic keratosis (AK) are common lesions in light-skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major disease burden, especially among the elderly. To establish an evidence-based framework for clinical decision making, the guideline “actinic keratosis and cutaneous squamous cell carcinoma” was updated and expanded by the topics cutaneous squamous cell carcinoma in situ (Bowen's disease) and actinic cheilitis. The guideline is aimed at dermatologists, general practitioners, ear nose and throat specialists, surgeons, oncologists, radiologists and radiation oncologists in hospitals and office-based settings, as well as other medical specialties, policy makers and insurance funds involved in the diagnosis and treatment of patients with AK and cSCC. A separate guideline exists for patients and their relatives. In this part, we will address aspects relating to epidemiology and etiology, diagnostics, surgical and systemic treatment of cutaneous squamous cell carcinoma (cSCC), surveillance and prevention.

Authors with CRIS profile

Involved external institutions

St. Josefskrankenhaus Germany (DE) Universitätsklinikum Carl Gustav Carus Dresden Germany (DE) Centroderm GmbH Germany (DE) Johannes Wesling Klinikum Minden Germany (DE) Eberhard Karls Universität Tübingen Germany (DE) Ruhr-Universität Bochum (RUB) Germany (DE) Universitätsklinikum Essen Germany (DE) Diakonie Klinikum GmbH Germany (DE) Klinikum der Universität München Germany (DE) Deutsche Krebsgesellschaft (DKG) Germany (DE) Universitätsmedizin der Johannes Gutenberg-Universität Mainz Germany (DE) Elbe Kliniken Stade-Buxtehude Germany (DE) Universitätsklinikum Augsburg Germany (DE) Martin-Luther-Universität Halle-Wittenberg (MLU) Germany (DE) Universitätsklinikum Schleswig-Holstein (UKSH) Germany (DE) Klinikum Osnabrück Germany (DE) Universitätsklinikum Leipzig Germany (DE) Ruprecht-Karls-Universität Heidelberg Germany (DE) Charité - Universitätsmedizin Berlin Germany (DE) Klinikum Dortmund Germany (DE) Carol Davila University of Medicine and Pharmacy / Universitatea de Medicină și Farmacie „Carol Davila” (UMF București) Romania (RO) Behandlungszentrum Knappschaftskrankenhaus Recklinghausen Germany (DE) Universität Osnabrück Germany (DE) Vivantes - Netzwerk für Gesundheit GmbH Germany (DE) LMU Klinikum Germany (DE) Robert Koch-Institut (RKI) Germany (DE) Universitätsklinikum Tübingen Germany (DE) Universitätsklinikum Regensburg Germany (DE) LWL-Klinikum Gütersloh Germany (DE) Deutsche Gesetzliche Unfallversicherung e.V. (DGUV) Germany (DE) Klinikum der Stadt Ludwigshafen am Rhein gGmbH Germany (DE) Klinikum Bremen-Ost Germany (DE) Philipps-Universität Marburg Germany (DE)

How to cite

APA:

Leiter, U., Heppt, M., Steeb, T., Alter, M., Amaral, T., Bauer, A.,... Berking, C. (2023). S3 guideline „actinic keratosis and cutaneous squamous cell carcinoma“ – update 2023, part 2: epidemiology and etiology, diagnostics, surgical and systemic treatment of cutaneous squamous cell carcinoma (cSCC), surveillance and prevention. Journal der Deutschen Dermatologischen Gesellschaft, 21(11), 1422-1433. https://doi.org/10.1111/ddg.15256

MLA:

Leiter, Ulrike, et al. "S3 guideline „actinic keratosis and cutaneous squamous cell carcinoma“ – update 2023, part 2: epidemiology and etiology, diagnostics, surgical and systemic treatment of cutaneous squamous cell carcinoma (cSCC), surveillance and prevention." Journal der Deutschen Dermatologischen Gesellschaft 21.11 (2023): 1422-1433.

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