Understanding the mechanism by which Gd(iii) coiled coils achieve magnetic resonance relaxivity - a study into the water coordination chemistry

Newton SL, Franke A, Zahl A, Molinaro G, Kenwright A, Smith DJ, Ivanovic-Burmazovic I, Britton MM, Peacock AF (2023)

Publication Type: Journal article

Publication year: 2023

Journal

Dalton Transactions Royal Society of Chemistry

DOI: 10.1039/d3dt02909c

Abstract

A class of Gd(iii) coiled coils achieve high MRI relaxivity, in part due to their slow rotational correlation time. However, extending their length is unable to further enhance performance, as the mechanism by which relaxivity is achieved is dominated by the presence of three inner sphere waters in rapid exchange, through an associative mechanism.

Authors with CRIS profile

Alicja Franke Lehrstuhl für Bioanorganische Chemie Achim Zahl Lehrstuhl für Chemistry of thin film materials Ivana Ivanovic-Burmazovic Lehrstuhl für Bioanorganische Chemie

Involved external institutions

University of Birmingham GB United Kingdom (GB) Durham University GB United Kingdom (GB)

How to cite

APA:

Newton, S.L., Franke, A., Zahl, A., Molinaro, G., Kenwright, A., Smith, D.J.,... Peacock, A.F. (2023). Understanding the mechanism by which Gd(iii) coiled coils achieve magnetic resonance relaxivity - a study into the water coordination chemistry. Dalton Transactions. https://dx.doi.org/10.1039/d3dt02909c

MLA:

Newton, S. L., et al. "Understanding the mechanism by which Gd(iii) coiled coils achieve magnetic resonance relaxivity - a study into the water coordination chemistry." Dalton Transactions (2023).

BibTeX: Download