Parameterization of voice onset for automatic assessment of Parkinson’s disease

Arias Vergara T, Schraut T, Orozco-Arroyave JR, Döllinger M (2022)

Publication Type: Journal article

Publication year: 2022


Original Authors: Tomas Arias-Vergara, Tobias Schraut, Juan R. Orozco-Arroyave, Michael Döllinger

Book Volume: 152

Pages Range: A140-A140

Issue: 4_Supplement

DOI: 10.1121/10.0015820


Acoustic analysis of Parkinson’s disease (PD) usually focuses on sustained oscillations of the vocal folds; however, the voice onset (transition from the rest state to a saturation value) is often neglected. In this study, we investigated the parameterization of the voice onset for the objective evaluation of PD. 50 PD patients (25 females) and 50 healthy controls (25 females) performed the sustained phonation of the vowels /ah/, /ih/, and /uh/. Three experts listened to the recordings and assessed the dysarthria level according to a modified version of the Frenchay dysarthria assessment scale (mFDA). We extracted the voice onset automatically, considering the time needed for the amplitude envelope of the acoustic signal to go from 10% up to 90% of the maximum value. Then, we computed filter bank features from the voice onset and pitch, loudness, and perturbation features from the sustained phonation. We performed automatic classification and regression analyses using support vector machines. We obtained a classification accuracy of 89% (AUC: 0.93) when we used feature importance analysis to reduce the feature set. In addition, the regression analysis showed a significant correlation (r: 0.583, p-value < 0.001) between the acoustic features and the mFDA scale. These results show the suitability of the voice onset for objective clinical evaluation of PD.

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Arias Vergara, T., Schraut, T., Orozco-Arroyave, J.R., & Döllinger, M. (2022). Parameterization of voice onset for automatic assessment of Parkinson’s disease. Journal of the Acoustical Society of America, 152, A140-A140.


Arias Vergara, Tomás, et al. "Parameterization of voice onset for automatic assessment of Parkinson’s disease." Journal of the Acoustical Society of America 152 (2022): A140-A140.

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