Clinical Results and Quality of Life After Transcortical Versus Transcallosal Resection of Adult Lateral and Third Ventricle Lesions: Long-Term Outcome

AlSharif M, Stroop R, Scholz M, Buchfelder M, Wiendieck K, Shiban E, Sommer B (2023)

Publication Type: Journal article

Publication year: 2023

Journal

World Neurosurgery Elsevier

DOI: 10.1016/j.wneu.2023.08.050

Abstract

Background: Resection of intraventricular tumors can be achieved using 2 main operative approaches: transcallosal or transcortical. This study aims to describe preoperative and postoperative factors as well as quality of life (QoL) based on long-term results in these patients. Methods: Patients underwent surgery of primary intraventricular lesions between 2007 and 2020 via a transcortical (group A) or transcallosal (group B) route. The main clinical parameters were completeness of resection, overall survival, surgical complications, postoperative neurologic deficits, and seizure rates. QoL was assessed using a modified questionnaire Short-Form 36 inventory. Results: Forty patients (19 women and 21 men) met the inclusion criteria. Group A consisted of 26 patients (12 women and 14 men; median age 45.5 years ± 16.7 standard deviation) and had lower preoperative tumor volume (confounder) compared with group B (7 women and 7 men; age 50.0 ± 17.4 years). Gross total resection was achieved in 65% in group A and 71% in group B. Follow-up was 7.8 ± 3.9 years. New seizures/permanent neurologic deficits occurred in 27%/15% (group A) and 29%/29% (group B) and surgical complications in 23% of patients. Group B had a higher degree of memory impairment (21%) compared with group A (10%). QoL impairment was present in both groups mainly regarding physical role function and mental health index. Conclusions: Keeping in mind the limitations, transcallosal surgery was associated with a higher probability of neurologic deficits and memory impairment in our series. However, it had fewer surgical complications with similar gross total resection and seizure rates.

Authors with CRIS profile

Michael Buchfelder Lehrstuhl für Neurochirurgie Björn Sommer Medizinische Fakultät

Involved external institutions

Niels-Stensen-Kliniken GmbH DE Germany (DE) Sana Kliniken AG DE Germany (DE) Kliniken Dr. Erler DE Germany (DE) Universitätsklinikum Augsburg DE Germany (DE)

How to cite

APA:

AlSharif, M., Stroop, R., Scholz, M., Buchfelder, M., Wiendieck, K., Shiban, E., & Sommer, B. (2023). Clinical Results and Quality of Life After Transcortical Versus Transcallosal Resection of Adult Lateral and Third Ventricle Lesions: Long-Term Outcome. World Neurosurgery. https://dx.doi.org/10.1016/j.wneu.2023.08.050

MLA:

AlSharif, Mustafa, et al. "Clinical Results and Quality of Life After Transcortical Versus Transcallosal Resection of Adult Lateral and Third Ventricle Lesions: Long-Term Outcome." World Neurosurgery (2023).

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