Quality of Life and Kidney Function in Older Adults: Prospective Data of the SCOPE Study
Artzi-Medvedik R, Kob R, Di Rosa M, Lattanzio F, Corsonello A, Yehoshua I, Roller-Wirnsberger RE, Wirnsberger GH, Mattace-Raso FU, Tap L, Gil PG, Formiga F, Moreno-González R, Kostka T, Guligowska A, Ärnlöv J, Carlsson AC, Freiberger E, Melzer I (2023)
Publication Type: Journal article
Publication year: 2023
Journal
Book Volume: 12
Article Number: 3959
Journal Issue: 12
DOI: 10.3390/jcm12123959
Abstract
A longitudinal alteration in health-related quality of life (HRQoL) over a two-year period and its association with early-stage chronic kidney disease (CKD) progression was investigated among 1748 older adults (>75 years). HRQoL was measured by the Euro-Quality of Life Visual Analog Scale (EQ-VAS) at baseline and at one and two years after recruitment. A full comprehensive geriatric assessment was performed, including sociodemographic and clinical characteristics, the Geriatric Depression Scale-Short Form (GDS-SF), Short Physical Performance Battery (SPPB), and estimated glomerular filtration rate (eGFR). The association between EQ-VAS decline and covariates was investigated by multivariable analyses. A total of 41% of the participants showed EQ-VAS decline, and 16.3% showed kidney function decline over the two-year follow-up period. Participants with EQ-VAS decline showed an increase in GDS-SF scores and a greater decline in SPPB scores. The logistic regression analyses showed no contribution of a decrease in kidney function on EQ-VAS decline in the early stages of CKD. However, older adults with a greater GDS-SF score were more likely to present EQ-VAS decline over time, whereas an increase in the SPPB scores was associated with less EQ-VAS decline. This finding should be considered in clinical practice and when HRQoL is used to evaluate health interventions among older adults.
Authors with CRIS profile
Robert Kob
Lehrstuhl für Innere Medizin (Geriatrie)
Ellen Freiberger
Lehrstuhl für Innere Medizin (Geriatrie)
Involved external institutions
Ben-Gurion University of the Negev (BGU) / אוניברסיטת בן-גוריון בנגב
Israel (IL)
Istituto Nazionale di Riposo e Cura per Anziani (IRCCS INRCA)
Italy (IT)
Maccabi Institute for Health Services Research
Israel (IL)
Medizinische Universität Graz
Austria (AT)
Erasmus University Medical Center (MC)
Netherlands (NL)
Hospital Clínico San Carlos
Spain (ES)
Bellvitge University Hospital / Hospital Universitari de Bellvitge
Spain (ES)
Medical University of Łódź / Uniwersytet Medyczny w Łodzi
Poland (PL)
Dalarna University College
Sweden (SE)
Karolinska Institute
Sweden (SE)
Israel (IL)
Istituto Nazionale di Riposo e Cura per Anziani (IRCCS INRCA)
Italy (IT)
Maccabi Institute for Health Services Research
Israel (IL)
Medizinische Universität Graz
Austria (AT)
Erasmus University Medical Center (MC)
Netherlands (NL)
Hospital Clínico San Carlos
Spain (ES)
Bellvitge University Hospital / Hospital Universitari de Bellvitge
Spain (ES)
Medical University of Łódź / Uniwersytet Medyczny w Łodzi
Poland (PL)
Dalarna University College
Sweden (SE)
Karolinska Institute
Sweden (SE)
How to cite
APA:
Artzi-Medvedik, R., Kob, R., Di Rosa, M., Lattanzio, F., Corsonello, A., Yehoshua, I.,... Melzer, I. (2023). Quality of Life and Kidney Function in Older Adults: Prospective Data of the SCOPE Study. Journal of Clinical Medicine, 12(12). https://dx.doi.org/10.3390/jcm12123959
MLA:
Artzi-Medvedik, Rada, et al. "Quality of Life and Kidney Function in Older Adults: Prospective Data of the SCOPE Study." Journal of Clinical Medicine 12.12 (2023).
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