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First application of dynamic oxygen-17 magnetic resonance imaging at 7 Tesla in a patient with early subacute stroke

Ebersberger L, Kratzer FJ, Potreck A, Niesporek SC, Keymling M, Nagel AM, Bendszus M, Wick W, Ladd ME, Schlemmer HP, Hoffmann A, Platt T, Paech D (2023)

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Publication Type: Journal article

Publication year: 2023

Journal

Book Volume: 17

Article Number: 1186558

DOI: 10.3389/fnins.2023.1186558

Abstract

Dynamic oxygen-17 (¹⁷O) magnetic resonance imaging (MRI) is an imaging method that enables a direct and non-invasive assessment of cerebral oxygen metabolism and thus potentially the distinction between viable and non-viable tissue employing a three-phase inhalation experiment. The purpose of this investigation was the first application of dynamic ¹⁷O MRI at 7 Tesla (T) in a patient with stroke. In this proof-of-concept experiment, dynamic ¹⁷O MRI was applied during ¹⁷O inhalation in a patient with early subacute stroke. The analysis of the relative ¹⁷O water (H2¹⁷O) signal for the affected stroke region compared to the healthy contralateral side revealed no significant difference. However, the technical feasibility of ¹⁷O MRI has been demonstrated paving the way for future investigations in neurovascular diseases.

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How to cite

APA:

Ebersberger, L., Kratzer, F.J., Potreck, A., Niesporek, S.C., Keymling, M., Nagel, A.M.,... Paech, D. (2023). First application of dynamic oxygen-17 magnetic resonance imaging at 7 Tesla in a patient with early subacute stroke. Frontiers in Neuroscience, 17. https://dx.doi.org/10.3389/fnins.2023.1186558

MLA:

Ebersberger, Louise, et al. "First application of dynamic oxygen-17 magnetic resonance imaging at 7 Tesla in a patient with early subacute stroke." Frontiers in Neuroscience 17 (2023).

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