Determining the resolution of a tracer for magnetic particle imaging by means of magnetic particle spectroscopy

Remmo A, Wiekhorst F, Kosch O, Lyer S, Unterweger H, Kratz H, Löwa N (2023)

Publication Type: Journal article

Publication year: 2023

Journal

RSC Advances Royal Society of Chemistry

Book Volume: 13

Pages Range: 15730-15736

Journal Issue: 23

DOI: 10.1039/d3ra01394d

Abstract

Magnetic particle imaging (MPI) is an imaging modality to quantitatively determine the three-dimensional distribution of magnetic nanoparticles (MNPs) administered as a tracer into a biological system. Magnetic particle spectroscopy (MPS) is the zero-dimensional MPI counterpart without spatial coding but with much higher sensitivity. Generally, MPS is employed to qualitatively evaluate the MPI capability of tracer systems from the measured specific harmonic spectra. Here, we investigated the correlation of three characteristic MPS parameters with the achievable MPI resolution from a recently introduced procedure based on a two-voxel-analysis of data taken from the system function acquisition that is mandatory in Lissajous scanning MPI. We evaluated nine different tracer systems and determined their MPI capability and resolution from MPS measurements and compared the results with MPI phantom measurements.

Authors with CRIS profile

Stefan Lyer Department of Otorhinolaryngology – Head and Neck Surgery Harald Unterweger Department of Otorhinolaryngology – Head and Neck Surgery

Involved external institutions

Physikalisch-Technische Bundesanstalt (PTB) DE Germany (DE) Charité - Universitätsmedizin Berlin DE Germany (DE)

How to cite

APA:

Remmo, A., Wiekhorst, F., Kosch, O., Lyer, S., Unterweger, H., Kratz, H., & Löwa, N. (2023). Determining the resolution of a tracer for magnetic particle imaging by means of magnetic particle spectroscopy. RSC Advances, 13(23), 15730-15736. https://doi.org/10.1039/d3ra01394d

MLA:

Remmo, Amani, et al. "Determining the resolution of a tracer for magnetic particle imaging by means of magnetic particle spectroscopy." RSC Advances 13.23 (2023): 15730-15736.

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