Riskfactors of Osteoporosis

Baum E, Rintelen B, Siggelkow H, Engelke K, Glueer CC, Thomasius F (2023)

Publication Type: Journal article

Publication year: 2023

Journal

Osteologie Hogrefe / Schattauer

DOI: 10.1055/a-2045-7163

Abstract

Aim In the context of the development of the guideline update on prophylaxis, diagnosis and therapy of osteoporosis in postmeopausal women and in men for German-speaking countries, the osteoporosis-typical fracture risk should be quantified as accurately as possible and according to new data.Methods Based on a systematic literature search, the author group identified risk factors for typical osteoporotic fractures-in this case, explicitly hip fractures and vertebral fractures. The results were pooled, evaluated, and prioritized with respect to their relevance for risk calculation, which in the future should be possible electronically in the form of a risk calculator.Results Particularly strong risk factors for hip fracture include previous fractures of various locations, as well as type 1 diabetes, glucocorticoid therapy, and some neurologic diseases. In persons older than 75 years, a timed-up-and-go test>15 seconds reflects very well the increased risk for several conditions that correlate with an increased propensity to fall. After fractures, the risk of further fractures in the following year is greatly increased, so the imminent fracture risk must also be considered. Here we report the current status of the fracture risk assessment and inclusion in the guideline, which reflects work in progress.Conclusion Due to the complexity of the individual influencing factors, risk estimation is best achieved with a validated, electronically available risk calculator. Interim results are presented here, and a paper version will also be provided in the guideline update for the transition phase.

Authors with CRIS profile

Klaus Engelke Lehrstuhl für Medizinische Physik und Mikrogewebetechnik

Involved external institutions

Philipps-Universität Marburg DE Germany (DE) Landesklinikum Stockerau AT Austria (AT) MVZ Endokrinologikum DE Germany (DE) Christian-Albrechts-Universität zu Kiel DE Germany (DE)

How to cite

APA:

Baum, E., Rintelen, B., Siggelkow, H., Engelke, K., Glueer, C.-C., & Thomasius, F. (2023). Riskfactors of Osteoporosis. Osteologie. https://doi.org/10.1055/a-2045-7163

MLA:

Baum, Erika, et al. "Riskfactors of Osteoporosis." Osteologie (2023).

BibTeX: Download