Natural and synthetic nanovectors for cancer therapy
Eftekhari A, Kryschi C, Pamies D, Gulec S, Ahmadian E, Janas D, Davaran S, Khalilov R (2023)
Publication Type: Journal article, Review article
Publication year: 2023
Journal
Book Volume: 7
Pages Range: 236-257
Journal Issue: 3
DOI: 10.7150/ntno.77564
Abstract
Nanomaterials have been extensively studied in cancer therapy as vectors that may improve drug delivery. Such vectors not only bring numerous advantages such as stability, biocompatibility, and cellular uptake but have also been shown to overcome some cancer-related resistances. Nanocarrier can deliver the drug more precisely to the specific organ while improving its pharmacokinetics, thereby avoiding secondary adverse effects on the not target tissue. Between these nanovectors, diverse material types can be discerned, such as liposomes, dendrimers, carbon nanostructures, nanoparticles, nanowires, etc., each of which offers different opportunities for cancer therapy. In this review, a broad spectrum of nanovectors is analyzed for application in multimodal cancer therapy and diagnostics in terms of mode of action and pharmacokinetics. Advantages and inconveniences of promising nanovectors, including gold nanostructures, SPIONs, semiconducting quantum dots, various nanostructures, phospholipid-based liposomes, dendrimers, polymeric micelles, extracellular and exome vesicles are summarized. The article is concluded with a future outlook on this promising field.
Authors with CRIS profile
Additional Organisation(s)
Involved external institutions
Université de Lausanne (UNIL)
Switzerland (CH)
Ege University / Ege Üniversitesi
Turkey (TR)
Silesian University of Technology Gliwice
Poland (PL)
Tabriz University of Medical Sciences (TBZMED) / دانشگاه علوم پزشکی تبریز
Iran, Islamic Republic of (IR)
Baku State University / Aserbaidschanische Staatliche Öl- und Industrie-Universität / Bakı Dövlət Universiteti
Azerbaijan (AZ)
Izmir Institute of Technology (IZTECH)
Turkey (TR)
Yeditepe University / Yeditepe Üniversitesi
Turkey (TR)
Switzerland (CH)
Ege University / Ege Üniversitesi
Turkey (TR)
Silesian University of Technology Gliwice
Poland (PL)
Tabriz University of Medical Sciences (TBZMED) / دانشگاه علوم پزشکی تبریز
Iran, Islamic Republic of (IR)
Baku State University / Aserbaidschanische Staatliche Öl- und Industrie-Universität / Bakı Dövlət Universiteti
Azerbaijan (AZ)
Izmir Institute of Technology (IZTECH)
Turkey (TR)
Yeditepe University / Yeditepe Üniversitesi
Turkey (TR)
How to cite
APA:
Eftekhari, A., Kryschi, C., Pamies, D., Gulec, S., Ahmadian, E., Janas, D.,... Khalilov, R. (2023). Natural and synthetic nanovectors for cancer therapy. Nanotheranostics, 7(3), 236-257. https://dx.doi.org/10.7150/ntno.77564
MLA:
Eftekhari, Aziz, et al. "Natural and synthetic nanovectors for cancer therapy." Nanotheranostics 7.3 (2023): 236-257.
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