Lithium Aluminium Hydride and Metallic Iron: A Powerful Team in Alkene and Arene Hydrogenation Catalysis
Knüpfer C, Färber C, Langer J, Harder S (2023)
Publication Type: Journal article
Publication year: 2023
Journal
DOI: 10.1002/anie.202219016
Abstract
Alkenes that normally do not react with LiAlH4 (3-hexene, cyclohexene, 1-Me-cyclohexene), can be reduced to the corresponding alkanes by a mixture of LiAlH4 and Fe0 (the iron was activated by Metal-Vapour-Synthesis). This alkene-to-alkane conversion with a stoichiometric quantity of LiAlH4/Fe0 does not need quenching with water or acids, implying that both H's originate from LiAlH4. The LiAlH4/Fe0 combination is also a remarkably potent cooperative catalyst for hydrogenation of multi-substituted alkenes and benzene or toluene. An induction period of circa two hours and the minimally required temperature of 120 °C, suggests that the actual catalyst is a combination of Fe0 and the decomposition product of LiAlH4 (LiH and Al0). A thermally pre-activated LiAlH4/Fe0 catalyst did not need an induction time and is also active at room temperature and 1 bar H2. A combination of AliBu3 and Fe0 is an even more active hydrogenation catalyst. Without pre-activation, tetra-substituted alkenes like Me2C=CMe2 and toluene could be fully hydrogenated.
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How to cite
APA:
Knüpfer, C., Färber, C., Langer, J., & Harder, S. (2023). Lithium Aluminium Hydride and Metallic Iron: A Powerful Team in Alkene and Arene Hydrogenation Catalysis. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.202219016
MLA:
Knüpfer, Christian, et al. "Lithium Aluminium Hydride and Metallic Iron: A Powerful Team in Alkene and Arene Hydrogenation Catalysis." Angewandte Chemie International Edition (2023).
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