Liver dysfunction in geriatric patients

Kasper P, Tacke F, Heppner HJ, Michels G (2023)

Publication Type: Journal article

Publication year: 2023

Journal

Die Gastroenterologie Springer

DOI: 10.1007/s11377-023-00686-3

Abstract

With increasing age in addition to alterations of the cardiovascular, neurocognitive and musculoskeletal systems, alterations also occur in hepatic organ function. As a result of morphological and functional age-related processes, progressive hepatic organ dysfunction can develop with increased vulnerability with respect to endogenous and exogenous noxious substances and impaired hepatic regenerative capacity. Frequent causes of liver dysfunction in the geriatric population include non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease, viral hepatitis, autoimmune hepatitis and drug-induced liver injury. The prompt initiation of adequate diagnostic measures for identification of the underlying etiology is important for timely initiation of appropriate treatment and to reduce the risk of progressive impairment of hepatic function and associated complications.

Authors with CRIS profile

Hans Jürgen Heppner Professur für Geriatrie

Involved external institutions

Charité - Universitätsmedizin Berlin DE Germany (DE) St.-Antonius-Hospital Eschweiler DE Germany (DE) Universität zu Köln DE Germany (DE)

How to cite

APA:

Kasper, P., Tacke, F., Heppner, H.J., & Michels, G. (2023). Liver dysfunction in geriatric patients. Die Gastroenterologie. https://dx.doi.org/10.1007/s11377-023-00686-3

MLA:

Kasper, Philipp, et al. "Liver dysfunction in geriatric patients." Die Gastroenterologie (2023).

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