Male-specific late effects in adult hematopoietic cell transplantation recipients: a systematic review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation

Phelan R, Im A, Hunter RL, Inamoto Y, Lupo-Stanghellini MT, Rovo A, Badawy SM, Burns L, Eissa H, Murthy HS, Prasad P, Sharma A, Suelzer E, Agrawal V, Aljurf M, Baker K, Basak GW, Buchbinder D, Defilipp Z, Grkovic LD, Dias A, Einsele H, Eisenberg ML, Epperla N, Farhadfar N, Flatau A, Gale RP, Greinix H, Hamilton BK, Hashmi S, Hematti P, Jamani K, Maharaj D, Murray J, Naik S, Nathan S, Pavletic S, Peric Z, Pulanic D, Ross R, Salonia A, Sanchez-Ortega I, Savani BN, Schechter T, Shah AJ, Smith SM, Snowden JA, Steinberg A, Tremblay D, Vij SC, Walker L, Wolff D, Yared JA, Schoemans H, Tichelli A (2022)

Publication Type: Journal article

Publication year: 2022

Journal

Book Volume: 57

Pages Range: 1150-1163

Journal Issue: 7

DOI: 10.1038/s41409-022-01591-z

Abstract

Male-specific late effects after hematopoietic cell transplantation (HCT) include genital chronic graft-versus-host disease (GvHD), hypogonadism, sexual dysfunction, infertility, and subsequent malignancies. They may be closely intertwined and cause prolonged morbidity and decreased quality of life after HCT. We provide a systematic review of male-specific late effects in a collaboration between transplant physicians, endocrinologists, urologists, dermatologists, and sexual health professionals through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research, and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. The systematic review summarizes incidence, risk factors, screening, prevention and treatment of these complications and provides consensus evidence-based recommendations for clinical practice and future research.

Involved external institutions

University of Pittsburgh United States (USA) (US) University of Colorado System United States (USA) (US) Ospedale San Raffaele (früher: Centro San Raffaele del Monte Tabor Foundation) Italy (IT) Universität Bern Switzerland (CH) Ann & Robert H. Lurie Children's Hospital of Chicago United States (USA) (US) Medical College of Wisconsin (MCW) United States (USA) (US) Mayo Clinic United States (USA) (US) Louisiana State University United States (USA) (US) St. Jude Children’s Research Hospital United States (USA) (US) City of Hope Medical Center United States (USA) (US) Duke University Medical Center United States (USA) (US) Wrocław Medical University / Uniwersytet Medyczny we Wrocławiu Poland (PL) Westchester Medical Center University Hospital (WMC) United States (USA) (US) Icahn School of Medicine at Mount Sinai United States (USA) (US) Cleveland Clinic United States (USA) (US) Tom Baker Cancer Centre Canada (CA) Universitätsklinikum Regensburg Germany (DE) University of Maryland United States (USA) (US) University Hospital Leuven (UZ) / Universitaire ziekenhuizen Leuven Belgium (BE) Universitätsspital Basel Switzerland (CH) National Cancer Centre Singapore (NCCS) Singapore (SG) King Faisal Specialist Hospital & Research Centre Saudi Arabia (SA) Children's Hospital of Orange County (CHOC) United States (USA) (US) Massachusetts General Hospital United States (USA) (US) Zagreb University Hospital Centre / Klinički bolnički centar Zagreb (KBC) Croatia (HR) Beth Israel Deaconess Medical Center (BIDMC) United States (USA) (US) Universitätsklinikum Würzburg Germany (DE) Stanford University United States (USA) (US) Ohio State University United States (USA) (US) University of Florida United States (USA) (US) Association of Cancer Online Resources (ACOR) United States (USA) (US) Imperial College London / The Imperial College of Science, Technology and Medicine United Kingdom (GB) University of Wisconsin - Madison United States (USA) (US) University of Calgary Canada (CA) South Florida Bone Marrow/Stem Cell Transplant Institute United States (USA) (US) Christie NHS Foundation Trust United Kingdom (GB) Penn State Cancer Institute United States (USA) (US) Rush University United States (USA) (US) National Cancer Institute (NCI) United States (USA) (US) University of Zagreb / Sveučilište u Zagrebu Croatia (HR) University of Sheffield United Kingdom (GB) Università Vita-Salute San Raffaele (UniSR) Italy (IT) Catalan Institute of Oncology / Institut Català d'Oncologia (ICO) Spain (ES) Vanderbilt University Medical Center United States (USA) (US) University of Toronto Canada (CA) Stanford Medicine United States (USA) (US)

How to cite

APA:

Phelan, R., Im, A., Hunter, R.L., Inamoto, Y., Lupo-Stanghellini, M.T., Rovo, A.,... Tichelli, A. (2022). Male-specific late effects in adult hematopoietic cell transplantation recipients: a systematic review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Bone Marrow Transplantation, 57(7), 1150-1163. https://doi.org/10.1038/s41409-022-01591-z

MLA:

Phelan, Rachel, et al. "Male-specific late effects in adult hematopoietic cell transplantation recipients: a systematic review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation." Bone Marrow Transplantation 57.7 (2022): 1150-1163.

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