Systems biology meets metabolism

Krumsiek J, Stückler F, Kastenmüller G, Theis FJ (2014)

Publication Type: Authored book

Publication year: 2014

Publisher: Springer New York

ISBN: 9781461416890

DOI: 10.1007/978-1-4614-1689-0_17

Abstract

In the preceding chapters many aspects of metabolite quantification and relation to trait and disease phenotypes have been described, in particular the linkage of intermediate metabolic traits to genetic heterogeneities. Although many analyses start on the genome-wide level, they end up picking out single polymorphisms or other variations and study these in detail. This reductionist approach is very common in molecular biology and has proven hugely successful over the past decades. In recent years however, a second paradigm has become increasingly popular, namely that of integrating multiple such analyses into larger ones commonly called models. This paradigm, nowadays, is known as systems biology and is expected to penetrate many classical molecular analyses.

Involved external institutions

Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (HMGU) / Helmholtz Munich DE Germany (DE)

How to cite

APA:

Krumsiek, J., Stückler, F., Kastenmüller, G., & Theis, F.J. (2014). Systems biology meets metabolism. Springer New York.

MLA:

Krumsiek, Jan, et al. Systems biology meets metabolism. Springer New York, 2014.

BibTeX: Download